Evidence map›Paper›PMID 32197581›Full record

ArticleBMC geriatrics2020

Predicting hospitalisation-associated functional decline in older patients admitted to a cardiac care unit with cardiovascular disease: a prospective cohort study.

Bastiaan Van Grootven, Anthony Jeuris, Maren Jonckers, Els Devriendt, Bernadette Dierckx de Casterlé, Christophe Dubois, Katleen Fagard, Marie-Christine Herregods, Miek Hornikx, Bart Meuris and 5 more

Open access · goldAbstract read
In one paragraph

Article in BMC geriatrics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 2 countries.

Bastiaan Van GrootvenResearch Foundation - Flanders (FWO), Brussels, Belgium.
Anthony JeurisDepartment of Public Health and Primary Care, KU Leuven - University of Leuven, Leuven, Belgium.
Maren JonckersDepartment of Cardiovascular Medicine, University Hospitals Leuven, Leuven, Belgium.
Els DevriendtDepartment of Geriatric Medicine, University Hospitals Leuven, Leuven, Belgium.
Bernadette Dierckx de CasterléDepartment of Public Health and Primary Care, KU Leuven - University of Leuven, Leuven, Belgium.
Christophe DuboisDepartment of Cardiovascular Medicine, University Hospitals Leuven, Leuven, Belgium.
Katleen FagardDepartment of Public Health and Primary Care, KU Leuven - University of Leuven, Leuven, Belgium.
Marie-Christine HerregodsDepartment of Cardiovascular Medicine, University Hospitals Leuven, Leuven, Belgium.
Miek HornikxDepartment of Rehabilitation Sciences, KU Leuven - University of Leuven, University Hospitals Leuven, Leuven, Belgium.
Bart MeurisDepartment of Cardiovascular Medicine, University Hospitals Leuven, Leuven, Belgium.
Steffen RexDepartment of Cardiovascular Sciences, KU Leuven - University of Leuven, Leuven, Belgium.
Jos TournoyDepartment of Public Health and Primary Care, KU Leuven - University of Leuven, Leuven, Belgium.
Koen MilisenDepartment of Public Health and Primary Care, KU Leuven - University of Leuven, Leuven, Belgium.
Johan FlamaingDepartment of Public Health and Primary Care, KU Leuven - University of Leuven, Leuven, Belgium.
Mieke DeschodtDepartment of Public Health and Primary Care, KU Leuven - University of Leuven, Leuven, Belgium. mieke.deschodt@kuleuven.be.
KU Leuven · BEResearch Foundation - Flanders · BEUniversity of Basel · CH

Funding

Internal funds, KU Leuven 22/15/028
6 · The paper itself

Abstract

backgroundUp to one in three of older patients who are hospitalised develop functional decline, which is associated with sustained disability, institutionalisation and death. This study developed and validated a clinical prediction model that identifies patients who are at risk for functional decline during hospitalisation. The predictive value of the model was compared against three models that were developed for patients admitted to a general medical ward.

methodsA prospective cohort study was performed on two cardiac care units between September 2016 and June 2017. Patients aged 75 years or older were recruited on admission if they were admitted for non-surgical treatment of an acute cardiovascular disease. Hospitalisation-associated functional decline was defined as any decrease on the Katz Index of Activities of Daily Living between hospital admission and discharge. Predictors were selected based on a review of the literature and a prediction score chart was developed based on a multivariate logistic regression model.

resultsA total of 189 patients were recruited and 33% developed functional decline during hospitalisation. A score chart was developed with five predictors that were measured on hospital admission: mobility impairment = 9 points, cognitive impairment = 7 points, loss of appetite = 6 points, depressive symptoms = 5 points, use of physical restraints or having an indwelling urinary catheter = 5 points. The score chart of the developed model demonstrated good calibration and discriminated adequately (C-index = 0.75, 95% CI (0.68-0.83) and better between patients with and without functional decline (chi

conclusionFunctional decline is a prevalent complication and can be adequately predicted on hospital admission. A score chart can be used in clinical practice to identify patients who could benefit from preventive interventions. Independent external validation is needed.

Indexed as

Activities of Daily LivingAgedAged, 80 and overAgingCardiovascular DiseasesCohort StudiesCritical CareFemaleGeriatric AssessmentHospitalizationHumansInpatientsMalePredictive Value of TestsProspective StudiesRisk FactorsAgedCohortFunctionalGeriatricPredictionPrognosis

Identifiers

PMID32197581
PMCPMC7082946
OpenAlexW3012631759

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.