Evidence map›Paper›PMID 32197477›Full record

ReviewInternational journal of molecular sciences2020

Hepatitis C Virus Entry: An Intriguingly Complex and Highly Regulated Process.

Che C Colpitts, Pei-Ling Tsai, Mirjam B Zeisel

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. Hepatitis B virus entry, assembly, and egress.Microbiology and molecular biology reviews : MMBR · 2024
    Review
  10. Review
  11. Review
  12. After the Storm: Persistent Molecular Alterations Following HCV Cure.International journal of molecular sciences · 2024
    Review
  13. Article
  14. Review
  15. Review
  16. Virus-Associated Nephropathies: A Narrative Review.International journal of molecular sciences · 2022
    Review
  17. Review
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Che C ColpittsDepartment of Biomedical and Molecular Sciences, Queen's University, Kingston, ON K7L 3N6, Canada.
Pei-Ling TsaiDepartment of Biomedical and Molecular Sciences, Queen's University, Kingston, ON K7L 3N6, Canada.
Mirjam B ZeiselCancer Research Center of Lyon (CRCL), UMR Inserm 1052 CNRS 5286 Mixte CLB, Université de Lyon 1 (UCBL1), 69003 Lyon, France.

Funding

Agence Nationale de la Recherche Impulsion IdEx Lyon ANR-16-IDEX-0005Institut National de la Santé et de la Recherche Médicale InsermLigue Contre le Cancer PPE 2018Queen's University Research initiation grantUniversité de Lyon UdL
6 · The paper itself

Abstract

Hepatitis C virus (HCV) is a major cause of chronic hepatitis and liver disease worldwide. Its tissue and species tropism are largely defined by the viral entry process that is required for subsequent productive viral infection and establishment of chronic infection. This review provides an overview of the viral and host factors involved in HCV entry into hepatocytes, summarizes our understanding of the molecular mechanisms governing this process and highlights the therapeutic potential of host-targeting entry inhibitors.

Indexed as

Hepatitis C, ChronicHepatocytesHost-Pathogen InteractionsVirus InternalizationHepacivirusHumanscell-to-cell transmissionendocytosisfusionhepatitis C virushepatocyteviral entry

Identifiers

PMID32197477
PMCPMC7140000

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.