Evidence map›Paper›PMID 32197448›Full record

ArticleBiomolecules2020

2,3,4',5-Tetrahydroxystilbene-2-

Tien-Yuan Wu, Jia-Ni Lin, Zi-Yao Luo, Chuan-Jen Hsu, Jen-Shu Wang, Hung-Pin Wu

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Telomere Length and Hearing Loss: A Two-Sample Mendelian Randomization.International journal of environmental research and public health · 2022
    Pooled it
  2. Autophagy in Sensorineural Hearing Loss: Jekyll or Hyde?International journal of molecular sciences · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. The Role of Nrf2 in Hearing Loss.Frontiers in pharmacology · 2021
    Review
  10. Otoprotective Effect of 2,3,4',5-Tetrahydroxystilbene-2-Molecules (Basel, Switzerland) · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Tien-Yuan WuDepartment of Pharmacology, School of Medicine, College of Medicine, Tzu Chi University, Hualien 970, Taiwan.ORCID 0000-0002-5205-4567
Jia-Ni LinDepartment of Otolaryngology Head and Neck Surgery, Taichung Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Taichung 427, Taiwan.
Zi-Yao LuoDepartment of Otolaryngology Head and Neck Surgery, Taichung Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Taichung 427, Taiwan.
Chuan-Jen HsuDepartment of Otolaryngology Head and Neck Surgery, Taichung Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Taichung 427, Taiwan.ORCID 0000-0002-7548-7736
Jen-Shu WangSchool of Medicine, Tzu Chi University, Hualien 970, Taiwan.
Hung-Pin WuDepartment of Otolaryngology Head and Neck Surgery, Taichung Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Taichung 427, Taiwan.ORCID 0000-0003-3336-6319
Tzu Chi University · TWTaipei Tzu Chi Hospital · TW

Funding

Ministry of Science and Technology, Taiwan MOST 108-2314-B-320-003Taichung Tzu Chi Hospital, Buddhist Medical Foundation TCMF-MP 108-01-01
6 · The paper itself

Abstract

Oxidative stress plays a critical role in the pathogenesis of hearing loss, and 2,3,4',5-tetrahydroxystilbene-2-

Indexed as

AnimalsAntioxidantsAutophagyCochleaGlucosidesHydrogen PeroxideMiceNF-E2-Related Factor 2Oxidative StressSignal TransductionStilbenes2,3,5,4'-tetrahydroxystilbene 2-O-glucopyranosideAntioxidantsGlucosidesHydrogen PeroxideNfe2l2 protein, mouseNF-E2-Related Factor 2Stilbenes2,3,4′,5-tetrahydroxystilbene-2-O-β-D-glucoside (THSG), mouse cochlear UB/OC-2 cellsapoptosisautophagynucleus factor erythroid 2-related factor 2 (Nrf2)

Identifiers

PMID32197448
PMCPMC7175305
OpenAlexW3012265423

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.