Evidence map›Paper›PMID 32197426›Full record

ArticleMolecules (Basel, Switzerland)2020

Identification of Interleukin-8-Reducing Lead Compounds Based on SAR Studies on Dihydrochalcone-Related Compounds in Human Gingival Fibroblasts (HGF-1 cells) In Vitro.

Katharina Schueller, Joachim Hans, Stefanie Pfeiffer, Jessica Walker, Jakob P Ley, Veronika Somoza

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Discovery of Gingipains andFoods (Basel, Switzerland) · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Katharina SchuellerDepartment of Physiological Chemistry, Faculty of Chemistry, University of Vienna, Althanstraße 14, 1090 Vienna, Austria.
Joachim HansSymrise AG, Mühlenfeldstraße, 37603 Holzminden, Germany.
Stefanie PfeifferDepartment of Physiological Chemistry, Faculty of Chemistry, University of Vienna, Althanstraße 14, 1090 Vienna, Austria.
Jessica WalkerDepartment of Physiological Chemistry, Faculty of Chemistry, University of Vienna, Althanstraße 14, 1090 Vienna, Austria.
Jakob P LeySymrise AG, Mühlenfeldstraße, 37603 Holzminden, Germany.
Veronika SomozaDepartment of Physiological Chemistry, Faculty of Chemistry, University of Vienna, Althanstraße 14, 1090 Vienna, Austria.
University of Vienna · ATSymrise (Germany) · DELeibniz-Institute for Food Systems Biology at the Technical University of Munich · DE

Funding

Christian Doppler Forschungsgesellschaft CD-Labor für Bioaktive Aromastoffe
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Anti-Inflammatory AgentsChalconesLeadCell LineFibroblastsGingivaHumansInterleukin-8LipopolysaccharidesPeriodontal DiseasesPorphyromonas gingivalisAnti-Inflammatory AgentsChalconesCXCL8 protein, humandihydrochalconeInterleukin-8LeadLipopolysaccharidesdihydrochalconesHGF-1 cellsIL-8inflammationstructure–activity relationship

Identifiers

PMID32197426
PMCPMC7144391
OpenAlexW3010956124

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.