Evidence map›Paper›PMID 32197408›Full record

Trial reportNutrients2020

Quality of Life: Psychological Symptoms-Effects of a 2-Month Healthy Diet and Nutraceutical Intervention; A Randomized, Open-Label Intervention Trial (RISTOMED).

Isabelle Bourdel-Marchasson, Rita Ostan, Sophie C Regueme, Alessandro Pinto, Florence Pryen, Zoubida Charrouf, Patrizia d'Alessio, Claire Roubaud Baudron, Florent Guerville, Jessica Durrieu and 3 more

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07180485 (The Effectiveness of Whole Body Vibration Training in Improving Brain Activity, Bone Mineral Density, Quality of Life, and Biomarkers for the Older People With Dynapenic Abdominal Obesity), which is not on this map. Cited by 8 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 3 pooled it
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07180485 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

The Effectiveness of Whole Body Vibration Training in Improving Brain Activity, Bone Mineral Density, Quality of Life, and Biomarkers for the Older People With Dynapenic Abdominal Obesity

TypeinterventionalSponsorDalin Tzu Chi General HospitalRan2025 to 2027Enrolled120ConditionsDynapenia, Abdominal ObesityArmswhole body vibration training, control group
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 3 syntheses or guidelines pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Review
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  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 9 institutions in 5 countries.

Isabelle Bourdel-MarchassonCRMSB UMR 5536, Université Bordeaux/CNRS, F-33000 Bordeaux, France.
Rita OstanDepartment of Experimental, Diagnostic and Specialty Medicine (DIMES), University of Bologna, 40126 Bologna, Italy.
Sophie C ReguemeCHU Bordeaux, Pôle de gérontologie, Bordeaux, F-33000 Bordeaux, France.
Alessandro PintoExperimental Medicine Department, Sapienza University of Rome, 00185 Rome, Italy.
Florence PryenMendes SA, Via Giacometti 1 - CH-6900 Lugano, Switzerland.
Zoubida CharroufDepartment of Chemistry, University Mohammed V, BP 1014, Rabat, Morocco.
Patrizia d'AlessioAISA (Anti-Inflammatory Senescence Actives) Therapeutics, 94807 Villejuif, France.
Claire Roubaud BaudronCHU Bordeaux, Pôle de gérontologie, Bordeaux, F-33000 Bordeaux, France.ORCID 0000-0003-0870-0979
Florent GuervilleCHU Bordeaux, Pôle de gérontologie, Bordeaux, F-33000 Bordeaux, France.
Jessica DurrieuCHU Bordeaux, Pôle de gérontologie, Bordeaux, F-33000 Bordeaux, France.
Lorenzo M DoniniExperimental Medicine Department, Sapienza University of Rome, 00185 Rome, Italy.
Claudio FranceschiDepartment of Experimental, Diagnostic and Specialty Medicine (DIMES), University of Bologna, 40126 Bologna, Italy.
Luzia ValentiniDepartment Gastroenterology and Hepatology, Charité Universitätsmedizin Berlin, 10117 Berlin, Germany.ORCID 0000-0002-4313-0441
Centre Hospitalier Universitaire de Bordeaux · FRSapienza University of Rome · ITCentre National de la Recherche Scientifique · FRCharité - Universitätsmedizin Berlin · DEGenopole (France) · FRInserm · FRMohammed V University · MAN. I. Lobachevsky State University of Nizhny Novgorod · RUUniversity of Bologna · IT

Funding

FP7 Research for the Benefit of SMEs 222230
6 · The paper itself

Abstract

Depression symptoms and lower health-related quality of life (HRQoL) are associated with inflammation. This multicenter dietary intervention was shown to reduce inflammation in older people. This was the main outcome. Here, we describe the effects on HRQoL, anxiety, and depressive symptoms according to inflammation status. Overall, 125 healthy older subjects (65-80 year) were recruited (Italy, France, and Germany) and randomized into four arms (A, Healthy diet (HD); B, HD plus De Simone Formulation probiotic blend; C, HD plus AISA d-Limonene; D, HD plus Argan oil). The HD was weight maintaining, rich in antioxidant vitamins, polyphenols, polyunsaturated fatty acids (n6: n3 ratio = 3:1), and fiber. Data on inflammatory parameters, mental (MCS) and physical (PCS) component summaries of HRQoL (SF-36), anxiety symptoms (STAI state), and depressive symptoms (CES-D) were collected before and after 56 days of intervention. Body fat mass proportion (BFM) was considered a co-variable. A decrease of CES-D score was seen in the four arms (A: -40.0%,

Indexed as

Dietary SupplementsDiet, HealthyQuality of LifeAgedAged, 80 and overDepressionFemaleHumansMaledepressive symptomsinflammagingnutraceuticalsquality of life

Identifiers

PMID32197408
PMCPMC7146172
OpenAlexW3011946977

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.