Evidence map›Paper›PMID 32197295›Full record

ArticleInternational journal of molecular sciences2020

Hyaluronic Acid Reduces Bacterial Fouling and Promotes Fibroblasts' Adhesion onto Chitosan 2D-Wound Dressings.

Ilaria Silvestro, Mariangela Lopreiato, Anna Scotto d'Abusco, Valerio Di Lisio, Andrea Martinelli, Antonella Piozzi, Iolanda Francolini

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 52 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. An Overview of Wound Dressing Materials.Pharmaceuticals (Basel, Switzerland) · 2024
    Review
  9. Review
  10. Article
  11. Review
  12. Review
  13. Recent Advances in Nanozymes for Bacteria-Infected Wound Therapy.International journal of nanomedicine · 2022
    Review
  14. Review
  15. Versatile Use of Chitosan and Hyaluronan in Medicine.Molecules (Basel, Switzerland) · 2021
    Review
  16. Article
  17. Visualization of the Relationship Between Hyaluronic Acid and Wound Healing: A Bibliometric Analysis.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Ilaria SilvestroDepartment of Chemistry, Sapienza University of Rome, Piazzale A. Moro, 5, 00185 Rome, Italy.
Mariangela LopreiatoDepartment of Biochemical Sciences, Sapienza University of Rome, Piazzale A. Moro, 5, 00185 Rome, Italy.ORCID 0000-0002-6850-0437
Anna Scotto d'AbuscoDepartment of Biochemical Sciences, Sapienza University of Rome, Piazzale A. Moro, 5, 00185 Rome, Italy.ORCID 0000-0002-3323-6015
Valerio Di LisioDepartment of Chemistry, Sapienza University of Rome, Piazzale A. Moro, 5, 00185 Rome, Italy.
Andrea MartinelliDepartment of Chemistry, Sapienza University of Rome, Piazzale A. Moro, 5, 00185 Rome, Italy.
Antonella PiozziDepartment of Chemistry, Sapienza University of Rome, Piazzale A. Moro, 5, 00185 Rome, Italy.ORCID 0000-0002-4792-0520
Iolanda FrancoliniDepartment of Chemistry, Sapienza University of Rome, Piazzale A. Moro, 5, 00185 Rome, Italy.ORCID 0000-0002-0180-2334
Sapienza University of Rome · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Wound healing is a dynamic process that can be seriously delayed by many factors including infectious complications. The development of dressings with intrinsic wound healing activity and/or releasing bioactive compounds may help with addressing such an issue. In this study, hyaluronic acid (HA) at different percentages (1-35%) was used to modify chitosan (CS) biological and physico-chemical properties in order to obtain 2D-matrices able to promote healing and protect from infection. HA incorporation in the CS matrix decreased film transparency and homogeneity, but improved film water uptake and surface wettability. The water vapor transmission rate (WVTR) increased up to a 5% HA content, where it reached the highest value (672 g/m

Indexed as

BandagesChitosanHyaluronic AcidMembranes, ArtificialBacterial AdhesionCell AdhesionCells, CulturedFibroblastsHumansMaleStaphylococcus epidermidisChitosanHyaluronic AcidMembranes, Artificialchitosanfibroblasts adhesionhyaluronic acidStaphylococcus epidermidiswound dressings

Identifiers

PMID32197295
PMCPMC7139607
OpenAlexW3010686389

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.