Evidence map›Paper›PMID 32197050›Full record

ArticleAmerican journal of respiratory and critical care medicine2020

Localization of Macrophages in the Human Lung via Design-based Stereology.

Patrick S Hume, Sophie L Gibbings, Claudia V Jakubzick, Rubin M Tuder, Douglas Curran-Everett, Peter M Henson, Bradford J Smith, William J Janssen

Open access · greenAbstract read
In one paragraph

Article in American journal of respiratory and critical care medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers.

0numbers the graph read from it
0cells of the map it votes in
64citing papers in PubMed
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

64 citing papers in PubMed, 98 citations in OpenAlex.

  1. IL-9R/Arg1 pathway promotes polyamine metabolism in human airway macrophages.The Journal of allergy and clinical immunology · 2026
    Article
  2. Alternative splicing of toll-like receptor pathway mRNAs in lung immune cells from patients with ARDS.American journal of physiology. Lung cellular and molecular physiology · 2026
    Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Review
  8. Article
  9. Review
  10. Nanoparticle-Based Pulmonary Immune Engineering.Annual review of chemical and biomolecular engineering · 2025
    Review
  11. Article
  12. Chronic Hypoxia in an EXTrauterine Environment for Neonatal Development Impairs Lung Development.American journal of respiratory cell and molecular biology · 2025
    Article
  13. Review
  14. Article
  15. Review
  16. Review
  17. Article
  18. Stem cells, cell therapies, and bioengineering in lung biology and diseases 2023.American journal of physiology. Lung cellular and molecular physiology · 2024
    Review
  19. Article
  20. Article

4 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Patrick S HumeDivision of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, and.ORCID 0000-0002-5861-7375
Sophie L GibbingsDivision of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, and.
Claudia V JakubzickDepartment of Microbiology and Immunology, Dartmouth College, Hanover, New Hampshire.
Rubin M TuderDivision of Pulmonary Sciences and Critical Care Medicine.
Douglas Curran-EverettDivision of Biostatistics and Bioinformatics, National Jewish Health, Denver, Colorado.
Peter M HensonDivision of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, and.
Bradford J SmithDepartment of Biomedical Engineering, University of Colorado, Anschutz Medical Campus, Aurora, Colorado; and.ORCID 0000-0002-1583-6762
William J JanssenDivision of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, and.ORCID 0000-0002-6397-3454
SleepMed · USColorado School of Public Health · USDartmouth College · USPulmonary and Critical Care Associates · USUniversity of Colorado Anschutz Medical Campus · US

Funding

MULTIDISCIPLINARY RESPIRATORY DISEASES RESEARCH TRAININGT32HL007085 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI ELLEN L BURNHAM, LISA A MAIER · 1985 to 2026
$21.6M
Lung Macrophage Programming in Acute Lung InjuryR35HL140039 · NHLBI · NATIONAL JEWISH HEALTH · PI JANSSEN, WILLIAM · 2018 to 2024
$6.4M
Understanding the unique role endogenous APC subtypes play during the rejection of MAg-mismatched cellsR01HL115334 · NHLBI · NATIONAL JEWISH HEALTH · PI JAKUBZICK, CLAUDIA V · 2013 to 2020
$3.3M
Neutrophil Nox2 controls mononuclear cell functions in inflammation; role in CGDR01AI141389 · NIAID · NATIONAL JEWISH HEALTH · PI BRATTON, DONNA L, HENSON, PETER M · 2018 to 2022
$3.1M
Functional roles of human pulmonary DC's in the lung draining lymph nodesR01HL135001 · NHLBI · NATIONAL JEWISH HEALTH · PI JAKUBZICK, CLAUDIA V · 2017 to 2020
$2.3M
Stereologic Localization of Interstitial Macrophages in the Lungs of Smokers and NonsmokersF32HL145900 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI HUME, PATRICK SCOTT · 2019 to 2019
$70k
NHLBI NIH HHS F32 HL145900NHLBI NIH HHS R01 HL115334NHLBI NIH HHS R01 HL135001NHLBI NIH HHS R35 HL140039NHLBI NIH HHS T32 HL007085NIAID NIH HHS R01 AI141389
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdolescentAdultAgedCase-Control StudiesCell CountCigarette SmokingFemaleHumansImmunohistochemistryLectins, C-TypeLeukosialinLungMacrophages, AlveolarMaleMannose-Binding LectinsMannose ReceptorLectins, C-TypeLeukosialinMannose-Binding LectinsMannose ReceptorReceptors, Cell Surfacealveolarcigarette smokersemphysemainterstitialmorphometry

Identifiers

PMID32197050
PMCPMC7233346
OpenAlexW3011720767

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.