Evidence map›Paper›PMID 32197001›Full record

Observational studyESC heart failure2020

Elevated pre-transplant pulmonary vascular resistance is associated with early post-transplant atrial fibrillation and mortality.

Rasmus Rivinius, Matthias Helmschrott, Arjang Ruhparwar, Bastian Schmack, Fabrice F Darche, Dierk Thomas, Tom Bruckner, Andreas O Doesch, Hugo A Katus, Philipp Ehlermann

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in ESC heart failure, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 36 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Rasmus RiviniusDepartment of Cardiology, Angiology and Pneumology, Heidelberg University Hospital, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany.
Matthias HelmschrottDepartment of Cardiology, Angiology and Pneumology, Heidelberg University Hospital, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany.
Arjang RuhparwarDepartment of Cardiac Surgery, Heidelberg University Hospital, Heidelberg, Germany.
Bastian SchmackDepartment of Cardiac Surgery, Heidelberg University Hospital, Heidelberg, Germany.
Fabrice F DarcheDepartment of Cardiology, Angiology and Pneumology, Heidelberg University Hospital, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany.
Dierk ThomasDepartment of Cardiology, Angiology and Pneumology, Heidelberg University Hospital, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany.
Tom BrucknerInstitute for Medical Biometry and Informatics, University of Heidelberg, Heidelberg, Germany.
Andreas O DoeschDepartment of Cardiology, Angiology and Pneumology, Heidelberg University Hospital, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany.
Hugo A KatusDepartment of Cardiology, Angiology and Pneumology, Heidelberg University Hospital, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany.
Philipp EhlermannDepartment of Cardiology, Angiology and Pneumology, Heidelberg University Hospital, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany.
University Hospital Heidelberg · DEHeidelberg University · DEAsklepios · DEGerman Center for Infection Research · DEGerman Centre for Cardiovascular Research · DE

Funding

Deutsche Gesellschaft für Kardiologie-Herz und Kreislaufforschung Research ScholarshipMedizinischen Fakultät Heidelberg, Universität Heidelberg Physician Scientist Program
6 · The paper itself

Abstract

aimsSeverely elevated pre-transplant pulmonary vascular resistance (PVR) has been linked to adverse effects after heart transplantation (HTX). The impact of a moderately increased PVR before HTX on post-transplant outcomes remains uncertain. The aim of this study was to investigate the effects of an elevated pre-transplant PVR ≥ 300 dyn·s·cm METHODS AND

resultsThis observational retrospective single-centre study included 561 patients receiving HTX at Heidelberg Heart Center between 1989 and 2015. Patients were stratified by degree of pre-transplant PVR. Analyses covered demographics, post-transplant medication, mortality and causes of death after HTX, early post-transplant atrial fibrillation (AF), and length of the initial hospital stay after HTX. Ninety-four patients (16.8%) had a PVR ≥ 300 dyn·s·cm

conclusionsElevated pre-transplant PVR ≥ 300 dyn·s·cm

Indexed as

Atrial FibrillationHeart TransplantationVascular ResistanceAdultFemaleHumansLungMaleMiddle AgedProspective StudiesRetrospective StudiesAtrial fibrillationHeart transplantationLength of initial hospital stayMortalityPulmonary vascular resistance

Identifiers

PMID32197001
PMCPMC7083465
OpenAlexW3012491465

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.