ArticleInternational wound journal2020
Evaluation of mortality risk factors in diabetic foot infections.
Article in International wound journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 39 citations in OpenAlex.
- Clinical applications of machine learning for infection assessment in diabetic foot ulcers.Frontiers in physiology · 2026Review
- Microbiological profile and antimicrobial resistance in diabetic foot infections: a cross-sectional study from a low- to middle-income country.Scientific reports · 2025Article
- Explainable machine learning for differential diagnosis of diabetic foot infection and osteomyelitis: a two-center study and clinically applicable web calculator using routine blood biomarkers.BMC medical informatics and decision making · 2025Article
- Increased risk of major adverse cardiovascular events in patients with deep and infected diabetes-related foot ulcers.Diabetologia · 2025Article
- Unravelling the cardio-renal-metabolic-foot connection in people with diabetes-related foot ulceration: a narrative review.Cardiovascular diabetology · 2024Review
- Microbial profile of diabetic foot osteomyelitis from the northwest of England.Clinical diabetes and endocrinology · 2024Article
- [Development and Validation of a Risk Prediction Model for Prolonged Hospitalization in Patients With Diabetic Foot Ulcers].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2024Article
- Independent association of history of diabetic foot with all-cause mortality in patients with type 2 diabetes: the Renal Insufficiency And Cardiovascular Events (RIACE) Italian Multicenter Study.Cardiovascular diabetology · 2024Observational
- Evaluating Classification Systems of Diabetic Foot Ulcer Severity: A 12-Year Retrospective Study on Factors Impacting Survival.Healthcare (Basel, Switzerland) · 2023Article
- Diabetic foot infection caused by bacteria of the Burkholderia cepacia complex: report of an unusual case and a scoping literature review.Revista do Instituto de Medicina Tropical de Sao Paulo · 2022Article
- Virulent and multidrug-resistant Klebsiella pneumoniae from clinical samples in Balochistan.International wound journal · 2021Article
- Exploring the barriers of patients with diabetic foot complications in China: a qualitative interview study.Annals of translational medicine · 2021Article
- Evaluation of mortality risk factors in diabetic foot infections.International wound journal · 2020Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Identifying risk factors for mortality is crucial in the management of diabetic foot syndrome. We aimed to evaluate risk factors for mortality in patients with diabetic foot infection (DFI). A retrospective chart review was conducted on 401 patients from 2010 through 2019. Our primary endpoint was in-hospital mortality. Patients were divided into two groups according to the outcome (survival or death). Clinical data were compared between the two groups statistically. A total of 401 patients were enrolled in the study, 280 (69.8%) of them were male and the mean age was 59.6 ± 11.1 years. The mean follow-up period was 23.7 ± 22.9 months. In-hospital mortality rate was 3%. Univariate analysis indicated that ischaemic wound (P = .023), hindfoot infection (P = .038), whole foot infection (P = .010), peripheral arterial disease (P = .024), high leucocyte levels (>12 040 K/μL) (P = .001), high thrombocyte levels (>378 000 K/μL) (P < 0.001), high C-reactive protein levels (>8.81 mg/dL) (P = .022), and polymicrobial growth in deep tissue culture (P = .041) were significant parameters in predicting mortality. In multivariate analysis, peripheral arterial disease (odds ratio [OR]: 13.430, 95% confidence interval [Cl]: 1.129-59.692; P = .040), high thrombocyte levels (OR: 1.000, 95% Cl: 1.000-1.000; P = .022), and polymicrobial growth in deep tissue culture (OR: 7.790, 95% Cl: 1.592-38.118; P = .011) were independent risk factors for mortality. In conclusion, peripheral arterial disease, high thrombocyte levels, and polymicrobial growth in deep tissue culture were independent risk factors for mortality in DFI.
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