Evidence map›Paper›PMID 32196744›Full record

ArticleJournal of clinical laboratory analysis2020

Procalcitonin as a prognostic marker of patients with acute ischemic stroke.

Ling Yan, Shuling Wang, Lanlan Xu, Zhen Zhang, Pu Liao

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical laboratory analysis, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

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  6. Review
  7. Correlation analysis between serum procalcitonin and infarct volume in young patients with acute cerebral infarction.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ling YanDepartment of Clinical Laboratory, Chongqing General Hospital, Chongqing, China.
Shuling WangDepartment of Clinical Laboratory, Chongqing General Hospital, Chongqing, China.
Lanlan XuDepartment of Clinical Laboratory, Chongqing General Hospital, Chongqing, China.
Zhen ZhangDepartment of Clinical Laboratory, Chongqing General Hospital, Chongqing, China.
Pu LiaoDepartment of Clinical Laboratory, Chongqing General Hospital, Chongqing, China.ORCID https://orcid.org/0000-0002-8884-7059
Chongqing Emergency Medical Center · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe information on mortality after an acute stroke patient is still limited.

objectivesThe aim of this study was to investigate the prognostic potential of procalcitonin (PCT) serum levels in acute ischemic stroke.

methodsA total of 748 patients were enrolled in this study. Prognostic potential of PCT was evaluated by Kaplan-Meier analysis and multivariable Cox hazard regression analyses.

resultsProcalcitonin levels were found to be significantly higher in acute ischemic stroke patients who died in 30 days than those who survived. Univariate logistic regression analysis showed that PCT was significantly associated with 30-day mortality, and Cox regression analysis revealed that PCT was a strong predictor of 30-day overall mortality. Kaplan-Meier analysis revealed that overall cumulative 30-day mortality was significantly higher in those with PCT levels >1.5 ng/mL when compared to those with PCT levels <1.5 ng/mL.

conclusionsProcalcitonin is a significant independent prognostic marker of 30-day mortality after the one set of acute ischemic stroke.

Indexed as

AgedBiomarkersFemaleHumansIschemic StrokeKaplan-Meier EstimateMaleMiddle AgedProcalcitoninPrognosisProportional Hazards ModelsRetrospective StudiesBiomarkersProcalcitonin

Identifiers

PMID32196744
PMCPMC7370743
OpenAlexW3010755043

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.