Evidence map›Paper›PMID 32196526›Full record

Trial reportPloS one2020

Concurrently wasted and stunted 6-59 months children admitted to the outpatient therapeutic feeding programme in Karamoja, Uganda: Prevalence, characteristics, treatment outcomes and response.

Gloria A Odei Obeng-Amoako, Henry Wamani, Joel Conkle, Richmond Aryeetey, Joanita Nangendo, Ezekiel Mupere, Joan N Kalyango, Mark Myatt, André Briend, Charles A S Karamagi

Abstract readClinical TrialMulticenter Study
In one paragraph

Trial report in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Gloria A Odei Obeng-AmoakoSchool of Medicine, Clinical Epidemiology Unit, College of Health Sciences, Makerere University, Kampala, Uganda.ORCID 0000-0001-5004-3701
Henry WamaniDepartment of Community Health and Behavioural Sciences, School of Public Health, College of Health Sciences, Makerere University, Kampala, Uganda.
Joel ConkleHealth and Nutrition Section, UNICEF Namibia, Windhoek, Namibia.
Richmond AryeeteySchool of Public Health, University of Ghana, Legon, Ghana.
Joanita NangendoSchool of Medicine, Clinical Epidemiology Unit, College of Health Sciences, Makerere University, Kampala, Uganda.
Ezekiel MupereDepartment of Paediatrics and Child Health, College of Health Sciences, Makerere University, Kampala, Uganda.
Joan N KalyangoSchool of Medicine, Clinical Epidemiology Unit, College of Health Sciences, Makerere University, Kampala, Uganda.
Mark MyattBrixton Health, Wales, United Kingdom.
André BriendSchool of Medicine, Centre for Child Health Research, University of Tampere, Tampere, Finland.
Charles A S KaramagiSchool of Medicine, Clinical Epidemiology Unit, College of Health Sciences, Makerere University, Kampala, Uganda.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study assessed the prevalence of concurrently wasted and stunted (WaSt) children, their characteristics, treatment outcomes and response; and factors associated with time to recovery among children aged 6-59 months admitted to Outpatient Therapeutic Care (OTC) in Karamoja, Uganda. We conducted a retrospective cohort study with data from January 2016 to October 2017 for children admitted to nine OTCs in Karamoja. We defined wasted, stunted and underweight as 2.0 Z-scores below the median per WHO growth standards and < 12.5 cm for low Mid-Upper Arm Circumference (MUAC). WaSt was defined as concurrently wasted and stunted. Out of 788 eligible children included in the analysis; 48.7% (95% CI; 45.2-52.2) had WaSt. WaSt was common among males; 56.3% (95% CI; 51.3-61.3). Median age was 18 months in WaSt versus 12 months in non-WaSt children (p < 0.001). All WaSt children were underweight; and more severely wasted than non-WaSt children. During recovery, WaSt children gained weight more rapidly than non-WaSt children (2.2g/kg/day vs. 1.7g/kg/day). WaSt children had lower recovery rate (58.0% vs. 65.4%; p = 0.037). The difference in median time of recovery between WaSt and non-WaSt children (63 days vs. 56 days; p = 0.465) was not significant. Factors associated with time to recovery were children aged 24-59 months (aHR = 1.30; 95% CI;1.07-1.57;), children with MUAC 10.5-11.4 cm (aHR = 2.03; 95% CI; 1.55-2.66), MUAC ≥ 11.5 cm at admission (aHR = 3.31; 95% CI; 2.17-5.02) and living in Moroto (aHR = 3.34; 95% CI; 2.60-4.30) and Nakapiripirit (aHR = 1.95; 95% CI; 1.51-2.53) districts. The magnitude of children with WaSt in OTC shows that existing therapeutic feeding protocols could be used to detect and treat WaSt children. Further research is needed to identify and address the factors associated with sub-optimal recovery in WaSt children for effective OTC programming in Karamoja.

Indexed as

Ambulatory CareEnteral NutritionWasting SyndromeChild, PreschoolFemaleHumansInfantMalePrevalenceUganda

Identifiers

PMID32196526
PMCPMC7083304

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.