Evidence map›Paper›PMID 32195661›Full record

ArticleJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine2020

Cotard parasomnia: le délire de negation that occur during the sleep-wake dissociation?

Valentina Gnoni, Sean Higgins, Alexander David Nesbitt, Danielle Wasserman, Iain Duncan, Adam Birdseye, Laura Pérez-Carbonell, Panagis Drakatos, Michaelis Koutramanidis, Luigi Ferini-Strambi and 2 more

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Dreaming conundrum.Journal of sleep research · 2025
    Review
  2. Consciousness in non-REM-parasomnia episodes.Journal of sleep research · 2025
    Article
  3. Article
  4. Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Valentina GnoniSleep and Brain Plasticity Centre, Department of Neuroimaging, Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, United Kingdom.
Sean HigginsSleep and Brain Plasticity Centre, Department of Neuroimaging, Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, United Kingdom.
Alexander David NesbittSleep and Brain Plasticity Centre, Department of Neuroimaging, Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, United Kingdom.
Danielle WassermanSleep and Brain Plasticity Centre, Department of Neuroimaging, Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, United Kingdom.
Iain DuncanSleep Disorders Centre, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom.
Adam BirdseyeSleep Disorders Centre, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom.
Laura Pérez-CarbonellSleep Disorders Centre, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom.
Panagis DrakatosSleep Disorders Centre, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom.
Michaelis KoutramanidisDepartment of Neurology, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom.
Luigi Ferini-StrambiSleep Disorders Center, Department of Clinical Neurosciences, Università Vita-Salute San Raffaele, Milan, Italy.
Guy Doron LeschzinerSleep and Brain Plasticity Centre, Department of Neuroimaging, Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, United Kingdom.
Ivana RosenzweigSleep and Brain Plasticity Centre, Department of Neuroimaging, Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, United Kingdom.
Guy's and St Thomas' NHS Foundation Trust · GBKing's College London · GBVita-Salute San Raffaele University · IT

Funding

Wellcome Trust 103952/Z/14/Z
6 · The paper itself

Abstract

None: Unpleasant dreamlike mentation can occur during non-rapid eye movement parasomnias, leading to associated panic attacks. The mentations are rarely remembered and are likely underreported. However, they may lead to significant personal distress and, if not addressed, may contribute to poorer clinical outcomes. Cotard le délire de negation are very rare nihilistic delusions, historically described with psychotic disorders. Their association with a variety of neurologic disorders, including migraine and cluster-headache, has also been reported. Here we present three cases of Cotard parasomnia during which distinct states of consciousness defined by nihilistic ideation occurred. Patients described believing they are dead or dying, while unable to perceive or experience their bodies in whole, or in part, as their own. A source analysis of the electroencephalographic fingerprint of these mentations suggests right-hemispheric hypoactivity subsequent to confusional arousals. Mechanistically, an aberrant activation of two major intrinsic brain networks of wakefulness, the salience network and the default mode network, is argued.

Indexed as

ParasomniasSleep Arousal DisordersBrainDreamsElectroencephalographyHumansCotard delusiondefault mode networkEEGmajor intrinsic networksnon-REM parasomniasalience networksleepsleep-wake transition

Identifiers

PMID32195661
PMCPMC7849668
OpenAlexW3011911548

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.