Evidence map›Paper›PMID 32195580›Full record

ArticleACS nano2020

Ions and Water Dancing through Atom-Scale Holes: A Perspective toward "Size Zero".

Jothi Priyanka Thiruraman, Paul Masih Das, Marija Drndić

Erratum issuedAbstract read
In one paragraph

Article in ACS nano, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Tailoring KAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Funding

Enzyme-less DNA base discrimination using solid-state nanopores with high-frequency integrated detection electronicsR01HG009189 · NHGRI · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI DRNDIC, MARIJA, SHEPARD, KENNETH L · 2016 to 2018
$1.2M
DNA Sequencing with novel 2D FET-nanopore devicesR21HG010536 · NHGRI · UNIVERSITY OF PENNSYLVANIA · PI DRNDIC, MARIJA · 2019 to 2020
$624k
NHGRI NIH HHS R01 HG009189NHGRI NIH HHS R21 HG010536
6 · The paper itself

Abstract

We provide an overview of atom-scale apertures in solid-state membranes, from "pores" and "tubes" to "channels", with characteristic sizes comparable to the sizes of ions and water molecules. In this regime of ∼1 nm diameter pores, water molecules and ions are strongly geometrically confined: the size of water molecules (∼0.3 nm) and the size of "hydrated" ions in water (∼0.7-1 nm) are similar to the pore diameters, physically limiting the ion flow through the hole. The pore sizes are comparable to the classical Debye screening length governing the spatial range of electrostatic interaction, ∼0.3 to 1 nm for 1 to 0.1 M KCl. In such small structures, charges can be unscreened, leading to new effects. We discuss experiments on ∼1 nm diameter nanopores, with a focus on carbon nanotube pores and ion transport studies. Finally, we present an outlook for artificial "size zero" pores in the regime of small diameters and small thicknesses. Beyond mimicking protein channels in nature, solid-state pores may offer additional possibilities where sensing and control are performed at the pore, such as in electrically and optically addressable solid-state materials.

Identifiers

PMID32195580
PMCPMC9463116

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.