Evidence map›Paper›PMID 32195457›Full record

ArticleJHEP reports : innovation in hepatology2020

Ying Hu, Hui-Xin Liu, Prasant Kuma Jena, Lili Sheng, Mohamed R Ali, Yu-Jui Yvonne Wan

Open access · goldAbstract read
In one paragraph

Article in JHEP reports : innovation in hepatology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 1 synthesis or guideline pooled it, 60 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. The Role of microRNA-22 in Metabolism.International journal of molecular sciences · 2025
    Review
  8. Review
  9. Review
  10. Article
  11. Oligonucleotide therapies for nonalcoholic steatohepatitis.Molecular therapy. Nucleic acids · 2024
    Review
  12. Review
  13. Review
  14. Article
  15. Review
  16. Review
  17. Review
  18. Review
  19. Article
  20. miR-22 gene therapy treats HCC by promoting anti-tumor immunity and enhancing metabolism.Molecular therapy : the journal of the American Society of Gene Therapy · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Ying HuDepartment of Pathology and Laboratory Medicine, University of California Davis Health, Sacramento, CA 95817, United States of America.
Hui-Xin LiuDepartment of Pathology and Laboratory Medicine, University of California Davis Health, Sacramento, CA 95817, United States of America.
Prasant Kuma JenaDepartment of Pathology and Laboratory Medicine, University of California Davis Health, Sacramento, CA 95817, United States of America.
Lili ShengDepartment of Pathology and Laboratory Medicine, University of California Davis Health, Sacramento, CA 95817, United States of America.
Mohamed R AliDepartment of Surgery, University of California Davis Health, Sacramento, CA 95817, United States of America.
Yu-Jui Yvonne WanDepartment of Pathology and Laboratory Medicine, University of California Davis Health, Sacramento, CA 95817, United States of America.
University of California, Davis · US

Funding

Liver Cancer Therapy by MiR-22 and Its InducersR01CA222490 · NCI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI WAN, YU-JUI YVONNE · 2018 to 2023
$2.1M
Gut microbiota-derived signaling in liver carcinogenesis and cancer treatmentR50CA243787 · NCI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI HU, YING · 2019 to 2023
$795k
NCI NIH HHS R01 CA222490NCI NIH HHS R50 CA243787
6 · The paper itself

Abstract

BACKGROUND &

aimsMetabolism supports cell proliferation and growth. Surprisingly, the tumor suppressor

methodsThe relationship between

resultsThe levels of

conclusionThe simultaneous induction of LAY SUMMARY: This study examines the metabolic role of a tumor suppressor,

Indexed as

3'-UTR, 3' untranslated regionalcoholic steatosisALP, alkaline phosphataseALT, alanine aminotransferaseCD, control dietFGF21, fibroblast growth factor 21FXR, farnesoid X receptorGLP-1, glucagon-like peptideHDAC, histone deacetylaseinsulin sensitivityITT, insulin tolerance testLPS, lipopolysaccharidemetabolic syndromenon-alcoholic steatohepatitisNPCs, non-parenchymal cellsobeticholic acidOCA, obeticholic acidPFUs, plaque-forming unitsPGC1α, PPAR-activated receptor-γ coactivator-1αPHHs, primary human hepatocytesPPREs, peroxisome proliferative-response elementsRARβ, retinoic acid receptor βRT-PCR, reverse transcription PCRSIRT1, sirtuin 1SteatosisWD, Western diet

Identifiers

PMID32195457
PMCPMC7078383
OpenAlexW3008891014

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.