Evidence map›Paper›PMID 32195362›Full record

ArticleNPJ digital medicine2020

Prediction of stress and drug craving ninety minutes in the future with passively collected GPS data.

David H Epstein, Matthew Tyburski, William J Kowalczyk, Albert J Burgess-Hull, Karran A Phillips, Brenda L Curtis, Kenzie L Preston

Abstract read
In one paragraph

Article in NPJ digital medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Observational
  4. Article
  5. Article
  6. Article
  7. Daily Life Assessment of Seven Alcohol-Use-Disorder Symptoms.Clinical psychological science : a journal of the Association for Psychological Science · 2026
    Article
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  9. Article
  10. Predicting Craving-Related Emotions among Opioid Use Disorder Patients: Preliminary Results.... International Conference on Wearable and Implantable Body Sensor Networks. International Conference on Wearable and Implantable Body Sensor Networks · 2025
    Article
  11. Article
  12. Article
  13. Momentary mindfulness versus distraction coping messages to reduce cannabis craving among young adults: A microrandomized trial.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2025
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Smartphone and Wearable Device-Based Digital Phenotyping to Understand Substance use and its Syndemics.Journal of medical toxicology : official journal of the American College of Medical Toxicology · 2024
    Article
  19. Pharmacokinetics-Informed Neural Network for Predicting Opioid Administration Moments with Wearable Sensors.Proceedings of the ... AAAI Conference on Artificial Intelligence. AAAI Conference on Artificial Intelligence · 2024
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

David H EpsteinIntramural Research Program, National Institute on Drug Abuse, 251 Bayview Blvd., Suite 200, Baltimore, MD 21224 USA.
Matthew TyburskiIntramural Research Program, National Institute on Drug Abuse, 251 Bayview Blvd., Suite 200, Baltimore, MD 21224 USA.
William J KowalczykIntramural Research Program, National Institute on Drug Abuse, 251 Bayview Blvd., Suite 200, Baltimore, MD 21224 USA.
Albert J Burgess-HullIntramural Research Program, National Institute on Drug Abuse, 251 Bayview Blvd., Suite 200, Baltimore, MD 21224 USA.
Karran A PhillipsIntramural Research Program, National Institute on Drug Abuse, 251 Bayview Blvd., Suite 200, Baltimore, MD 21224 USA.
Brenda L CurtisIntramural Research Program, National Institute on Drug Abuse, 251 Bayview Blvd., Suite 200, Baltimore, MD 21224 USA.
Kenzie L PrestonIntramural Research Program, National Institute on Drug Abuse, 251 Bayview Blvd., Suite 200, Baltimore, MD 21224 USA.

Funding

Real-Time Assessment of Drug Use, Along with Mental States and EnvironmentsZIADA000499 · NIDA · NATIONAL INSTITUTE ON DRUG ABUSE · PI EPSTEIN, DAVID · 2009 to 2025
$19.9M
Digital Markers in Relapse and RecoveryZIADA000628 · NIDA · NATIONAL INSTITUTE ON DRUG ABUSE · PI CURTIS, BRENDA · 2019 to 2025
$10.0M
New approaches to addiction treatmentZIADA000624 · NIDA · NATIONAL INSTITUTE ON DRUG ABUSE · PI EPSTEIN, DAVID · 2018 to 2025
$9.6M
6 · The paper itself

Abstract

Just-in-time adaptive interventions (JITAIs), typically smartphone apps, learn to deliver therapeutic content when users need it. The challenge is to "push" content at algorithmically chosen moments without making users trigger it with effortful input. We trained a randomForest algorithm to predict heroin craving, cocaine craving, or stress (reported via smartphone app 3x/day) 90 min into the future, using 16 weeks of field data from 189 outpatients being treated for opioid-use disorder. We used only one form of continuous input (along with person-level demographic data), collected passively: an indicator of environmental exposures along the past 5 h of movement, as assessed by GPS. Our models achieved excellent overall accuracy-as high as 0.93 by the end of 16 weeks of tailoring-but this was driven mostly by correct predictions of absence. For predictions of presence, "believability" (positive predictive value, PPV) usually peaked in the high 0.70s toward the end of the 16 weeks. When the prediction target was more rare, PPV was lower. Our findings complement those of other investigators who use machine learning with more broadly based "digital phenotyping" inputs to predict or detect mental and behavioral events. When target events are comparatively subtle, like stress or drug craving, accurate detection or prediction probably needs effortful input from users, not passive monitoring alone. We discuss ways in which accuracy is difficult to achieve or even assess, and warn that high overall accuracy (including high specificity) can mask the abundance of false alarms that low PPV reveals.

Indexed as

Disease-free survivalRisk factors

Identifiers

PMID32195362
PMCPMC7055250

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.