ArticleScience advances2020
Retinol-binding protein 2 (RBP2) binds monoacylglycerols and modulates gut endocrine signaling and body weight.
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Article in Science advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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22citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
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Who cites it
22 citing papers in PubMed, 31 citations in OpenAlex.
- Intracellular Retinoid-Binding Proteins (CRBP, CRALBP, CRABP) as Emerging Drug Targets in Retinal Disease.International journal of molecular sciences · 2026Review
- Tissue-specific roles of monoacylglycerol (MAG) in metabolic diseases.Immunometabolism (Cobham, Surrey) · 2026Review
- The Role of Intracellular Lipid-Binding Proteins in Digestive System Neoplasms.Current oncology (Toronto, Ont.) · 2025Review
- Recent evolution of the developing human intestine affects metabolic and barrier functions.Science (New York, N.Y.) · 2025Article
- Unraveling the complexities of diet induced obesity and glucolipid dysfunction in metabolic syndrome.Diabetology & metabolic syndrome · 2025Review
- Retinoids and retinoid-binding proteins: Unexpected roles in metabolic disease.Current topics in developmental biology · 2025Review
- Massive bowel resection modulates the expression of genes involved in lipid and cholesterol metabolism in rats.microPublication biology · 2024Article
- ARDS and aging: TYMS emerges as a promising biomarker and therapeutic target.Frontiers in immunology · 2024Article
- Dietary Vitamin A Affects the Function of Incretin-Producing Enteroendocrine Cells in Male Mice Fed a High-Fat Diet.The Journal of nutrition · 2023Article
- Goods and Bads of the Endocannabinoid System as a Therapeutic Target: Lessons Learned after 30 Years.Pharmacological reviews · 2023Review
- Human gut epithelium features recapitulated in MINERVA 2.0 millifluidic organ-on-a-chip device.APL bioengineering · 2023Article
- The Multifunctional Family of Mammalian Fatty Acid-Binding Proteins.Annual review of nutrition · 2023Review
- Impact of Intracellular Lipid Binding Proteins on Endogenous and Xenobiotic Ligand Metabolism and Disposition.Drug metabolism and disposition: the biological fate of chemicals · 2023Review
- Article
- Colitis Induces Sex-Specific Intestinal Transcriptomic Responses in Mice.International journal of molecular sciences · 2022Article
- Mechanisms of endocannabinoid transport in the brain.British journal of pharmacology · 2022Review
- Retinol-binding protein 2 (RBP2): More than just dietary retinoid uptake.Biochimica et biophysica acta. Molecular and cell biology of lipids · 2022Review
- Intestinal Enteroendocrine Cell Signaling: Retinol-binding Protein 2 and Retinoid Actions.Endocrinology · 2022Article
- When fat meets the gut-focus on intestinal lipid handling in metabolic health and disease.EMBO molecular medicine · 2022Review
- Probing predilection to Crohn's disease and Crohn's disease flares: A crowd-sourced bioinformatics approach.Journal of pathology informatics · 2022Article
Corrections and comments
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Authors and funding
16 authors at 5 institutions in 2 countries.
Seung-Ah LeeDepartment of Medicine, Institute of Human Nutrition, College of Physicians and Surgeons, Columbia University, New York, NY, USA.ORCID 0000-0002-9192-2849
Kryscilla Jian Zhang YangDepartment of Medicine, Institute of Human Nutrition, College of Physicians and Surgeons, Columbia University, New York, NY, USA.ORCID 0000-0003-4912-3397
Pierre-Jacques BrunDepartment of Medicine, Institute of Human Nutrition, College of Physicians and Surgeons, Columbia University, New York, NY, USA.ORCID 0000-0002-8526-5408
Josie A SilvaroliDepartment of Pharmacology, Case Western Reserve University, Cleveland, OH, USA.ORCID 0000-0002-4505-3670
Jason J YuenDepartment of Medicine, Institute of Human Nutrition, College of Physicians and Surgeons, Columbia University, New York, NY, USA.
Igor ShmarakovDepartment of Medicine, Institute of Human Nutrition, College of Physicians and Surgeons, Columbia University, New York, NY, USA.ORCID 0000-0002-4073-9585
Hongfeng JiangDepartment of Medicine, Institute of Human Nutrition, College of Physicians and Surgeons, Columbia University, New York, NY, USA.
Jun B FeranilDepartment of Medicine, Institute of Human Nutrition, College of Physicians and Surgeons, Columbia University, New York, NY, USA.
Xueting LiPhD Program in Nutritional and Metabolic Biology, Institute of Human Nutrition, College of Physicians and Surgeons, Columbia University, New York, NY, USA.ORCID 0000-0002-3801-8535
Atreju I LackeyDepartment of Nutritional Sciences and Rutgers Center for Lipid Research, Rutgers University, New Brunswick, NJ, USA.ORCID 0000-0002-7474-2766
Wojciech KrężelInstitut de Génétique et de Biologie Moléculaire et Cellulaire, U1258, CNRS, UMR 7104, Unistra, Illkirch 67404, France.ORCID 0000-0003-1605-3185
Rudolph L LeibelDepartment of Pediatrics, Institute of Human Nutrition, College of Physicians and Surgeons, Columbia University, New York, NY, USA.ORCID 0000-0002-6062-7222
Jenny LibienDepartment of Pathology, SUNY Downstate Medical Center, Brooklyn, NY, USA.ORCID 0000-0001-6291-4391
Judith StorchDepartment of Nutritional Sciences and Rutgers Center for Lipid Research, Rutgers University, New Brunswick, NJ, USA.ORCID 0000-0001-5482-1777
Marcin GolczakDepartment of Pharmacology, Case Western Reserve University, Cleveland, OH, USA.
William S BlanerDepartment of Medicine, Institute of Human Nutrition, College of Physicians and Surgeons, Columbia University, New York, NY, USA.ORCID 0000-0002-9847-7506
Columbia University · USCase Western Reserve University · USRutgers, The State University of New Jersey · USCentre National de la Recherche Scientifique · FRSUNY Downstate Health Sciences University · US
Funding
Translational Research Support CoreP30ES005022 · NIEHS · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI BRIAN T BUCKLEY · 1988 to 2026
$47.4MUser Training and OutreachP30GM124165 · NIGMS · CORNELL UNIVERSITY · PI STEVEN E EALICK · 2018 to 2026
$34.2MRESEARCH TRAININGP30DK026687 · NIDDK · ST. LUKE'S-ROOSEVELT INST FOR HLTH SCIS · PI Anthony W Ferrante, DYMPNA GALLAGHER · 1986 to 2026
$33.0MPOSTDOCTORAL TRAINING IN ARTERIOSCLEROSIS RESEARCHT32HL007343 · NHLBI · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI HENRY N GINSBERG, Muredach P Reilly · 1985 to 2026
$12.7MThe molecular genetic analysis of human obesityR01DK052431 · NIDDK · ROCKEFELLER UNIVERSITY · PI CHUNG, WENDY K, LEIBEL, RUDOLPH L · 1996 to 2020
$11.6MSupplement to DK-38389 Lipid Transport in the IntestineR01DK038389 · NIDDK · RUTGERS THE ST UNIV OF NJ NEW BRUNSWICK · PI SAMPATH, HARINI, STORCH, JUDITH · 1992 to 2025
$8.6MHormones: Molecular Mechanism of Action and FunctionsT32DK007328 · NIDDK · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI KOUSTENI, STAVROULA · 1986 to 2025
$7.8MNUTRITIONT32DK007647 · NIDDK · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI Anthony W Ferrante, Lori M Zeltser · 1990 to 2026
$7.4MPostprandial Vitamin AR01DK068437 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI BLANER, WILLIAM S · 2004 to 2023
$7.0MRBP2 Biology and PathobiologyR01DK122071 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI WILLIAM S BLANER, Marcin Bernard Golczak · 2019 to 2026
$4.6MRegulation of vitamin A metabolism in the eyeR01EY023948 · NEI · CASE WESTERN RESERVE UNIVERSITY · PI GOLCZAK, MARCIN BERNARD · 2014 to 2023
$3.8MPixel Array Detector for X-ray CrystallographyS10RR029205 · NCRR · CORNELL UNIVERSITY · PI EALICK, STEVEN E · 2010 to 2010
$1.8MNCRR NIH HHS S10 RR029205NEI NIH HHS R01 EY023948NHLBI NIH HHS T32 HL007343NIDDK NIH HHS P30 DK026687NIDDK NIH HHS R01 DK038389NIDDK NIH HHS R01 DK052431NIDDK NIH HHS R01 DK068437NIDDK NIH HHS R01 DK101251NIDDK NIH HHS R01 DK122071NIDDK NIH HHS T32 DK007328NIDDK NIH HHS T32 DK007647NIEHS NIH HHS P30 ES005022NIGMS NIH HHS P30 GM124165
Abstract
Expressed in the small intestine, retinol-binding protein 2 (RBP2) facilitates dietary retinoid absorption.
Indexed as
Body WeightSignal TransductionAnimalsDiet, High-FatGastric Inhibitory PolypeptideIntestinal MucosaMiceMice, KnockoutMonoglyceridesRetinol-Binding Proteins, CellularGastric Inhibitory PolypeptideMonoglyceridesRbp2 protein, mouseRetinol-Binding Proteins, Cellular
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.