Evidence map›Paper›PMID 32195339›Full record

ArticleScience advances2020

Exploiting species specificity to understand the tropism of a human-specific toxin.

K M Boguslawski, A N McKeown, C J Day, K A Lacey, K Tam, N Vozhilla, S Y Kim, M P Jennings, S B Koralov, N C Elde and 1 more

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
0.5field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 28 citations in OpenAlex.

  1. Review
  2. Review
  3. A promisingClinical and experimental vaccine research · 2025
    Review
  4. Article
  5. Integrated genomic and proteomic analysis of the mouse-adaptedCurrent research in microbial sciences · 2025
    Article
  6. Review
  7. The Translational Value of Rodent Models of Sepsis.American journal of respiratory and critical care medicine · 2024
    Article
  8. Article
  9. Article
  10. Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Review
  16. Article
  17. Article
  18. Review
  19. International journal of molecular sciences · 2020
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

K M BoguslawskiDepartment of Microbiology, New York University School of Medicine, New York, NY 10016, USA.ORCID 0000-0001-5297-6767
A N McKeownDepartment of Human Genetics, University of Utah School of Medicine, Salt Lake City, UT 84112, USA.
C J DayInstitute for Glycomics, Griffith University, Gold Coast, QLD 4222, Australia.ORCID 0000-0001-7953-4408
K A LaceyDepartment of Microbiology, New York University School of Medicine, New York, NY 10016, USA.ORCID 0000-0002-9242-0170
K TamDepartment of Microbiology, New York University School of Medicine, New York, NY 10016, USA.ORCID 0000-0003-0534-1691
N VozhillaDepartment of Microbiology, New York University School of Medicine, New York, NY 10016, USA.
S Y KimOffice of Collaborative Sciences, New York University School of Medicine, New York, NY 10016, USA.
M P JenningsInstitute for Glycomics, Griffith University, Gold Coast, QLD 4222, Australia.ORCID 0000-0002-1027-4684
S B KoralovDepartment of Pathology, New York University School of Medicine, New York, NY 10016, USA.ORCID 0000-0002-4843-3791
N C EldeDepartment of Human Genetics, University of Utah School of Medicine, Salt Lake City, UT 84112, USA.ORCID 0000-0002-0426-1377
V J TorresDepartment of Microbiology, New York University School of Medicine, New York, NY 10016, USA.ORCID 0000-0002-7126-0489
New York University · USGriffith University · AUUniversity of Utah · US

Funding

Vaccine FacilityP30CA016087 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI ADRIANA HEGUY · 1985 to 2026
$83.1M
MEDICAL SCIENTIST TRAININGT32GM007308 · NIGMS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI PHILIPS, MARK REID · 1985 to 2019
$23.2M
INFECTIOUS DISEASES &BASIC MICROBIOLOGICAL MECHANISMST32AI007180 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI WEISER, JEFFREY NEAL · 1985 to 2022
$8.9M
Mechanistic Studies Of The Staphylococcus aureus LukAB CytotoxinR01AI099394 · NIAID · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI Victor J. Torres · 2013 to 2026
$6.1M
Microbial triggers and molecular mechanisms of Th17 mediated airway inflammation-Resubmission-1R01HL125816 · NHLBI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI KORALOV, SERGEI BORISOVICH · 2015 to 2019
$3.3M
Mechanisms of mimicry underlying the evolution of a model poxvirusR01GM114514 · NIGMS · UNIVERSITY OF UTAH · PI ELDE, NELS C. · 2015 to 2019
$1.6M
NCI NIH HHS P30 CA016087NHLBI NIH HHS R01 HL125816NIAID NIH HHS HHSN272201400019CNIAID NIH HHS R01 AI099394NIAID NIH HHS T32 AI007180NIGMS NIH HHS R01 GM114514NIGMS NIH HHS T32 GM007308
6 · The paper itself

Abstract

Many pathogens produce virulence factors that are specific toward their natural host. Clinically relevant methicillin-resistant

Indexed as

AnimalsBacterial ProteinsBacterial ToxinsCD11b AntigenHL-60 CellsHumansLeukocidinsMethicillin-Resistant Staphylococcus aureusMiceMice, TransgenicStaphylococcal InfectionsVirulence FactorsBacterial ProteinsBacterial ToxinsCD11b AntigenITGAM protein, humanleukocidin AB, Staphylococcus aureusLeukocidinsVirulence Factors

Identifiers

PMID32195339
PMCPMC7065885
OpenAlexW3011915989

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.