Evidence map›Paper›PMID 32195332›Full record

ArticleNPJ breast cancer2020

The genetic architecture of breast papillary lesions as a predictor of progression to carcinoma.

Tanjina Kader, Kenneth Elder, Magnus Zethoven, Timothy Semple, Prue Hill, David L Goode, Niko Thio, Dane Cheasley, Simone M Rowley, David J Byrne and 8 more

Open access · goldAbstract read
In one paragraph

Article in NPJ breast cancer, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 34 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Papillary lesions of the breast.Virchows Archiv : an international journal of pathology · 2022
    Review
  11. Papillary neoplasms of the breast-reviewing the spectrum.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2021
    Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 5 institutions in 2 countries.

Tanjina Kader1Peter MacCallum Cancer Centre, Melbourne, VIC Australia.ORCID 0000-0002-1463-7593
Kenneth Elder3The Breast Service, The Royal Women's Hospital, Fitzroy, VIC Australia.
Magnus Zethoven1Peter MacCallum Cancer Centre, Melbourne, VIC Australia.
Timothy Semple1Peter MacCallum Cancer Centre, Melbourne, VIC Australia.
Prue Hill4Department of Anatomical Pathology, St Vincent's Hospital, Fitzroy, VIC Australia.
David L Goode1Peter MacCallum Cancer Centre, Melbourne, VIC Australia.
Niko Thio1Peter MacCallum Cancer Centre, Melbourne, VIC Australia.
Dane Cheasley1Peter MacCallum Cancer Centre, Melbourne, VIC Australia.ORCID 0000-0002-1170-4690
Simone M Rowley1Peter MacCallum Cancer Centre, Melbourne, VIC Australia.
David J Byrne1Peter MacCallum Cancer Centre, Melbourne, VIC Australia.ORCID 0000-0002-9258-3252
Jia-Min Pang1Peter MacCallum Cancer Centre, Melbourne, VIC Australia.
Islam M Miligy5Nottingham Breast Cancer Research Centre, Division of Cancer and Stem Cells, School of Medicine, University of Nottingham and Nottingham University Hospitals NHS Trust, City Hospital, Nottingham, UK.
Andrew R Green5Nottingham Breast Cancer Research Centre, Division of Cancer and Stem Cells, School of Medicine, University of Nottingham and Nottingham University Hospitals NHS Trust, City Hospital, Nottingham, UK.
Emad A Rakha5Nottingham Breast Cancer Research Centre, Division of Cancer and Stem Cells, School of Medicine, University of Nottingham and Nottingham University Hospitals NHS Trust, City Hospital, Nottingham, UK.
Stephen B Fox1Peter MacCallum Cancer Centre, Melbourne, VIC Australia.
G Bruce Mann3The Breast Service, The Royal Women's Hospital, Fitzroy, VIC Australia.
Ian G Campbell *1Peter MacCallum Cancer Centre, Melbourne, VIC Australia.ORCID 0000-0002-7773-4155
Kylie L Gorringe *1Peter MacCallum Cancer Centre, Melbourne, VIC Australia.
Peter MacCallum Cancer Centre · AUNottingham University Hospitals NHS Trust · GBRoyal Women's Hospital · AUThe University of Melbourne · AUSt Vincent's Hospital Melbourne · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intraductal papillomas (IDP) are challenging breast findings because of their variable risk of progression to malignancy. The molecular events driving IDP development and genomic features of malignant progression are poorly understood. In this study, genome-wide CNA and/or targeted mutation analysis was performed on 44 cases of IDP, of which 20 cases had coexisting ductal carcinoma in situ (DCIS), papillary DCIS or invasive ductal carcinoma (IDC). CNA were rare in pure IDP, but 69% carried an activating

Indexed as

Breast cancerCancer genetics

Identifiers

PMID32195332
PMCPMC7067788
OpenAlexW3011626518

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.