Evidence map›Paper›PMID 32195330›Full record

ArticleTransplantation direct2020

Incidence and Outcomes of Significant Weight Changes After Pancreas Transplant Alone.

Kurtis J Swanson, Emily Joachim, Annamalai Arunachalam, Fahad Aziz, Neetika Garg, Maha Mohamed, Arjang Djamali, Robert R Redfield, Dixon B Kaufman, Jon Odorico and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Transplantation direct, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Kurtis J SwansonDivision of Nephrology, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI.
Emily JoachimDivision of Nephrology, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI.
Annamalai ArunachalamDivision of Nephrology, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI.
Fahad AzizDivision of Nephrology, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI.
Neetika GargDivision of Nephrology, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI.
Maha MohamedDivision of Nephrology, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI.
Arjang DjamaliDivision of Nephrology, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI.
Robert R RedfieldDivision of Transplant Surgery, Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, WI.
Dixon B KaufmanDivision of Transplant Surgery, Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, WI.
Jon OdoricoDivision of Transplant Surgery, Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, WI.
Didier MandelbrotDivision of Nephrology, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI.
Sandesh ParajuliDivision of Nephrology, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI.
University of Wisconsin–Madison · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWeight change, primarily weight gain, is a common problem among solid organ transplant recipients. The incidence of weight gain or loss after successful pancreas transplant alone (PTA) and the effect on graft survival is unknown.

methodsThis was a single-center observational study among PTA recipients, transplanted at our center between January 1, 2005, and July 31, 2017, who had a functional pancreas graft for at least 1 year and documented weight change at the 1-year clinic visit.

resultsIn this cohort study of 105 PTA recipients, 28 had significant weight gain, 27 had significant weight loss, and the remaining 50 did not have significant weight change at 1-year posttransplant. When comparing the weight gain and no weight change groups, the weight gain cohort started to gain weight at 3 months posttransplant to 5 years or last follow up. Similarly, the weight loss group lost weight at 3 months posttransplant up to last follow up. Clinically significant weight gain or weight loss were not associated with uncensored or death censored graft failure in univariate regression and Kaplan-Meier survival analysis. Also, there were no significant differences between the groups in the glycated hemoglobin at last follow up.

conclusionsApproximately 50% of PTA recipients had a significant weight change at 1-year posttransplant, of which 25% gained significant weight and 25% loss. There was no significant difference in graft survival due to the significant weight changes. Further research is needed in this field.

Identifiers

PMID32195330
PMCPMC7056274
OpenAlexW3007356980

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.