Evidence map›Paper›PMID 32195246›Full record

ArticleFrontiers in cell and developmental biology2020

Reduction of Sphingosine Kinase 1 Phosphorylation and Activity in

Raj Kumar Sah, Soumya Pati, Monika Saini, Pon Arunachalam Boopathi, Sanjay Kumar Kochar, Dhanpat Kumar Kochar, Ashis Das, Shailja Singh

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cell and developmental biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Loss of sphingosine 1-phosphate receptor 3 gene function impairs injury-induced stromal angiogenesis in mouse cornea.Laboratory investigation; a journal of technical methods and pathology · 2021
    Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Raj Kumar SahSpecial Centre for Molecular Medicine, Jawaharlal Nehru University, New Delhi, India.
Soumya PatiDepartment of Life Sciences, School of Natural Sciences, Shiv Nadar University, Greater Noida, India.
Monika SainiSpecial Centre for Molecular Medicine, Jawaharlal Nehru University, New Delhi, India.
Pon Arunachalam BoopathiDepartment of Biological Sciences, Birla Institute of Technology and Science, Pilani, India.
Sanjay Kumar KocharDepartment of Medicine, Sardar Patel Medical College, Bikaner, India.
Dhanpat Kumar KocharSardar Patel Medical College, Bikaner, India.
Ashis DasDepartment of Biological Sciences, Birla Institute of Technology and Science, Pilani, India.
Shailja SinghSpecial Centre for Molecular Medicine, Jawaharlal Nehru University, New Delhi, India.
Jawaharlal Nehru University · INBirla Institute of Technology and Science, Pilani · INSardar Patel Medical College · INShiv Nadar University · IN

Funding

Using Next-Generation Genomics to Study Antimalarial Drug Resistance in IndiaU19AI089676 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI CARLTON, JANE M · 2010 to 2023
$22.6M
NIAID NIH HHS U19 AI089676
6 · The paper itself

Abstract

Sphingosine-1-phosphate (S1P), a bioactive lipid mediator is involved in an array of biological processes and linked to pathological manifestations. Erythrocyte is known as the major reservoir for S1P as they lack S1P-degrading enzymes (S1P lyase and S1P phosphohydrolase) and harbor sphingosine kinase-1 (SphK-1) essential for sphingosine conversion to S1P. Reduced S1P concentration in serum was correlated with disease severity in patients with

Indexed as

complicated malariaerythrocytesPlasmodium falciparumPlasmodium vivaxsphingosine-1-phosphatesphingosine kinase-1thrombocytopeniauncomplicated malaria

Identifiers

PMID32195246
PMCPMC7062701
OpenAlexW3010276407

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.