ArticleFrontiers in bioengineering and biotechnology2020
Optimization of Three-Level Cervical Hybrid Surgery to Prevent Adjacent Segment Disease: A Finite Element Study.
Article in Frontiers in bioengineering and biotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Comparison of hybrid surgeries for the treatment of three-level cervical degenerative disease: a systematic review and network meta-analysis.Frontiers in surgery · 2026Pooled it
- Different Center of Rotation Trajectories after Cervical Hybrid Surgery: A Minimum 7-Year Retrospective Comparison of Bryan and Mobi-C Prostheses.Global spine journal · 2026Article
- Non-contiguous three-level hybrid surgery with C2-3 cervical disc arthroplasty: a case report and literature review.Frontiers in surgery · 2025Article
- Main elements of current spine biomechanics research: model, installation and test data.Frontiers in bioengineering and biotechnology · 2025Review
- Biomechanical evaluation of four internal fixation systems for two-segment anterior cervical corpectomy and fusion: a finite element analysis.Frontiers in bioengineering and biotechnology · 2025Article
- Overloaded Vertebral Body Following Consecutive Three-Level Hybrid Surgery Comparing with Anterior Cervical Discectomy and Fusion.Orthopaedic surgery · 2024Article
- Article
- Anterior percutaneous full-endoscopic transcorporeal decompression for cervical disc herniation: a finite element analysis and long-term follow-up study.BMC musculoskeletal disorders · 2024Article
- Biomechanical Effects on the Prostheses and Vertebrae of Three-Level Hybrid Surgery: A Finite Element Study.Orthopaedic surgery · 2024Article
- Biomechanical Analysis of Hybrid Artificial Discs or Zero-Profile Devices for Treating 1-Level Adjacent Segment Degeneration in ACDF Revision Surgery.Neurospine · 2024Article
- Biomechanical study of anterior transpedicular root screw intervertebral fusion system of lower cervical spine: a finite element analysis.Frontiers in bioengineering and biotechnology · 2024Article
- Preliminary exploration of the biomechanical properties of three novel cervical porous fusion cages using a finite element study.BMC musculoskeletal disorders · 2023Article
- Biomechanical effects of hybrid constructions in the treatment of noncontinuous cervical spondylopathy: a finite element analysis.Journal of orthopaedic surgery and research · 2023Article
- Evaluating the biomechanical performance of Ti6Al4V volar plates in patients with distal radius fractures.Frontiers in bioengineering and biotechnology · 2023Article
- The influence of over-distraction on biomechanical response of cervical spine post anterior interbody fusion: a comprehensive finite element study.Frontiers in bioengineering and biotechnology · 2023Article
- Optimization of Spinal Reconstructions for Thoracolumbar Burst Fractures to Prevent Proximal Junctional Complications: A Finite Element Study.Bioengineering (Basel, Switzerland) · 2022Article
- Classification of three-level hybrid surgery for the treatment of cervical degenerative disc disease: a retrospective study of 108 patients.BMC surgery · 2022Article
- Factors Associated with Postoperative Rehospitalization in Patients with Cervical Disc Herniation.International journal of environmental research and public health · 2022Article
- Investigation into Cervical Spine Biomechanics Following Single, Multilevel and Hybrid Disc Replacement Surgery with Dynamic Cervical Implant and Fusion: A Finite Element Study.Bioengineering (Basel, Switzerland) · 2022Article
- Biomechanical feasibility of semi-rigid stabilization and semi-rigid lumbar interbody fusion: a finite element study.BMC musculoskeletal disorders · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hybrid surgery (HS) allows surgeons to tailor fusion and arthroplasty in the treatment of multiple-level cervical disc degeneration. However, the decision making of selecting either ACDF or ADR for each level in three-level HS remains controversial and has not been fully investigated. This study was aimed to optimize three-level cervical hybrid constructs by systematically investigating their biomechanical properties and their effect on adjacent levels. A finite element model of cervical spine (C2-C7) was developed, and eight C3-C6 surgical models including six HS were constructed. The range of motion (ROM) in flexion, extension, lateral bending, and axial rotation under 2.0 Nm moments with 30 N follower load were simulated. The von Mises stress, strain energy at the adjacent intervertebral disc (IVD) and force at the adjacent facet were calculated. The ROM of the hybrid constructs and adjacent levels was close to that of the intact spine. HS with arthroplasty performed at C5-6 had better performance in terms of ROM reduction at the inferior adjacent level (C6-7). Moreover, C-D-D and 3ADR had best performance in reducing the von Mises stress and strain energy at C6-7. All HS reduced the facet burden at both C2-3 and C6-7 levels. However, the major drawback of HS revealed here is that the effect of C6-7 protection is at the cost of increased C2-3 IVD burden. In conclusion, we recommend C-D-D and 3ADR for patient with C3-C6 disc degeneration without predisposing C2-3 condition. C-C-D could be a good alternative with a lower medical cost. This analysis guides the decision making in three-level cervical HS before future cadaver studies or human clinical trials.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.