ReviewCureus2020
Post-splenectomy Sepsis: A Review of the Literature.
Review in Cureus, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
66 citing papers in PubMed, 118 citations in OpenAlex.
- Laparoscopic Splenectomy for a Completely Infarcted Wandering Spleen After Prolonged Positional Abdominal Pain: A Case Report and Focused Literature Review.Clinical case reports · 2026Article
- Necrotizing Fasciitis Caused by Serotype 7C Streptococcus pneumoniae in Overwhelming Post-splenectomy Infection.Internal medicine (Tokyo, Japan) · 2026Article
- Article
- Evaluating functional hyposplenism in pediatric hodgkin lymphoma: the role of marginal zone b cells post-radiotherapy.BMC cancer · 2026Article
- From Hemolysis to Lupus: A Case of Evans Syndrome Revealing Systemic Autoimmunity.Clinical case reports · 2026Article
- Endoscopic ultrasound-guided cyanoacrylate therapy for gastric variceal bleeding secondary to sinistral portal hypertension: a retrospective case series.Frontiers in medicine · 2026Article
- The Splenectomy Paradox in Thalassemia: Reduced Transfusion Requirements vs. Accelerated Hepatic Fibrogenesis.Mediterranean journal of hematology and infectious diseases · 2026Article
- Hemorrhage from a pancreatic pseudocyst eroding the stomach, diaphragm, and splenic artery: a case report on integrated surgical and nursing management.AME case reports · 2026Article
- Culture-negative cryptogenic splenic abscess in an immunocompetent host with recurrent misdiagnosis as pleural effusion: a case report with a review of the literature.Frontiers in medicine · 2026Article
- Splenic PD-L1Research (Washington, D.C.) · 2026Article
- Learning curve and perioperative outcomes of robotic-assisted distal pancreatectomy: a single-center study.Journal of robotic surgery · 2025Article
- Article
- Clinical relevance of the compartments and lymphocyte subsets in the human spleen.Cell and tissue research · 2025Article
- Save or Remove the Accessory Spleen in Patient Candidates to Splenectomy for Lymphoproliferative Disorders: Rational and Literature Review.Clinical case reports · 2025Article
- Longterm efficacy of a patient focused intervention in patients with asplenia- a three year follow-up of the PrePPS trial.Infection · 2025Article
- Splenectomy in Onco-Hematologic Patients: A Retrospective Study of Early Complications and 1-Year Mortality.Cancers · 2025Article
- Evaluation of information available on the web to patients undergoing splenectomy in Japan.PEC innovation · 2025Article
- Uncovering Glucose-6-Phosphate Isomerase (GPI) Deficiency in a Five-Year-Old With Hemolytic Anemia in Bahrain.Cureus · 2025Article
- A painful twist: Wandering spleen with torsion and infarction: A case report.International journal of surgery case reports · 2025Article
- Severe Anaplasmosis with Multi-Organ Failure in a Patient with Splenectomy: A Case Report.Infectious disease reports · 2025Article
6 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The spleen is an intraperitoneal organ that performs vital hematological and immunological functions. It maintains both innate and adaptive immunity and protects the body from microbial infections. The removal of the spleen as a treatment method was initiated from the early 1500s for traumatic injuries, even before the physiology of spleen was properly understood. Splenectomy has therapeutic effects in many conditions such as sickle cell anemia, thalassemia, idiopathic thrombocytopenic purpura (ITP), Hodgkin's disease, and lymphoma. However, it increases the risk of infections and, in some cases, can lead to a case of severe sepsis known as overwhelming post-splenectomy infection (OPSI), which has a very high mortality rate. Encapsulated bacteria form a major proportion of the invading organisms, of which the most common is
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.