Evidence map›Paper›PMID 32194915›Full record

ArticleAmerican journal of translational research2020

Long noncoding RNA,

Ritu Chaudhary, Xuefeng Wang, Biwei Cao, Janis De La Iglesia, Jude Masannat, Feifei Song, Juan C Hernandez-Prera, Nicholas T Gimbrone, Robbert Jc Slebos, Christine H Chung

Open access · greenAbstract read
In one paragraph

Article in American journal of translational research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Ritu ChaudharyDepartment of Head and Neck-Endocrine Oncology, Moffitt Cancer Center Tampa, FL, USA.
Xuefeng WangDepartment of Biostatistics and Bioinformatics, Moffitt Cancer Center Tampa, FL, USA.
Biwei CaoDepartment of Biostatistics and Bioinformatics, Moffitt Cancer Center Tampa, FL, USA.
Janis De La IglesiaDepartment of Head and Neck-Endocrine Oncology, Moffitt Cancer Center Tampa, FL, USA.
Jude MasannatDepartment of Head and Neck-Endocrine Oncology, Moffitt Cancer Center Tampa, FL, USA.
Feifei SongDepartment of Head and Neck-Endocrine Oncology, Moffitt Cancer Center Tampa, FL, USA.
Juan C Hernandez-PreraDepartment of Pathology, Moffitt Cancer Center Tampa, FL, USA.
Nicholas T GimbroneDepartment of Head and Neck-Endocrine Oncology, Moffitt Cancer Center Tampa, FL, USA.
Robbert Jc SlebosDepartment of Head and Neck-Endocrine Oncology, Moffitt Cancer Center Tampa, FL, USA.
Christine H ChungDepartment of Head and Neck-Endocrine Oncology, Moffitt Cancer Center Tampa, FL, USA.
Moffitt Cancer Center · US

Funding

TRANSLATIONAL RESEARCHP30CA076292 · NCI · UNIVERSITY OF SOUTH FLORIDA · PI Christine O'Connell · 1998 to 2026
$93.5M
NCI NIH HHS P30 CA076292
6 · The paper itself

Abstract

Head and neck squamous cell carcinoma (HNSCC) is an aggressive epithelial malignancy characterized by frequent mutations and metastasis. Long noncoding RNAs (lncRNAs) have been implicated in tumorigenesis and serve as novel prognostic biomarkers in different cancers. To enhance our understanding of lncRNAs that may have biological significance in HNSCC and may serve as prognostic biomarkers, we globally profiled lncRNAs in HNSCC by analyzing the RNA-seq data from The Atlas of Noncoding RNAs in Cancer (TANRIC) database. Of 3576 lncRNAs, we identified 926 (higher-688, lower-238) lncRNAs with a 2-fold abundance difference among the forty HNSCC and paired adjacent normal tissue. We investigated differential abundance of lncRNAs based on

Indexed as

Head and neck squamous cell carcinoma (HNSCC)human papillomavirus (HPV)long noncoding RNAs (lncRNA)prognostic biomarkerRNA-seq

Identifiers

PMID32194915
PMCPMC7061833
OpenAlexW3012657569

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.