Evidence map›Paper›PMID 32194849›Full record

ReviewTheranostics2020

Using magnetic particle imaging systems to localize and guide magnetic hyperthermia treatment: tracers, hardware, and future medical applications.

Prashant Chandrasekharan, Zhi Wei Tay, Daniel Hensley, Xinyi Y Zhou, Barry Kl Fung, Caylin Colson, Yao Lu, Benjamin D Fellows, Quincy Huynh, Chinmoy Saayujya and 6 more

Open access · goldAbstract readReview
In one paragraph

Review in Theranostics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 76 papers.

0numbers the graph read from it
0cells of the map it votes in
76citing papers in PubMed
9.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

76 citing papers in PubMed, 185 citations in OpenAlex.

  1. Verification and validation in canine cadaver of an MPI-integrable RF head coil for magnetic particle hyperthermia.International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group · 2026
    Article
  2. Review
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  7. Chitosan-Coated FeMaterials (Basel, Switzerland) · 2025
    Article
  8. Review
  9. Computational Design of a Thermal Applicator for Brain Hyperthermia Controlled by Capacitor Positioning in Loop Coils.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2025
    Article
  10. Review
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  15. Microfabrication Technologies for Nanoinvasive and High-Resolution Magnetic Neuromodulation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Review
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16 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 1 institution in 1 country.

Prashant ChandrasekharanUniversity of California Berkeley, Department of Bioengineering, Berkeley, CA 94720, United States.
Zhi Wei TayUniversity of California Berkeley, Department of Bioengineering, Berkeley, CA 94720, United States.
Daniel HensleyMagnetic Insight, Inc., Alameda, CA 94501, United States.
Xinyi Y ZhouUniversity of California Berkeley, Department of Bioengineering, Berkeley, CA 94720, United States.
Barry Kl FungUniversity of California Berkeley, Department of Bioengineering, Berkeley, CA 94720, United States.
Caylin ColsonUniversity of California Berkeley, Department of Bioengineering, Berkeley, CA 94720, United States.
Yao LuUniversity of California Berkeley, Department of Bioengineering, Berkeley, CA 94720, United States.
Benjamin D FellowsUniversity of California Berkeley, Department of Bioengineering, Berkeley, CA 94720, United States.
Quincy HuynhDepartment of Electrical Engineering and Computer Sciences, University of California, Berkeley, CA 94720, United States.
Chinmoy SaayujyaDepartment of Electrical Engineering and Computer Sciences, University of California, Berkeley, CA 94720, United States.
Elaine YuMagnetic Insight, Inc., Alameda, CA 94501, United States.
Ryan OrendorffMagnetic Insight, Inc., Alameda, CA 94501, United States.
Bo ZhengUniversity of California Berkeley, Department of Bioengineering, Berkeley, CA 94720, United States.
Patrick GoodwillMagnetic Insight, Inc., Alameda, CA 94501, United States.
Carlos RinaldiUniversity of Florida, J. Crayton Pruitt Family Department of Biomedical Engineering and Department of Chemical Engineering, FL, 32611 United States.
Steven ConollyUniversity of California Berkeley, Department of Bioengineering, Berkeley, CA 94720, United States.
University of California, Berkeley · US

Funding

In Vivo Therapeutic Cell Tracking by Advanced Magnetic Particle ImagingR01EB024578 · NIBIB · UNIVERSITY OF CALIFORNIA BERKELEY · PI CONOLLY, STEVEN M · 2017 to 2020
$2.2M
Pre-clinical quantitation of ovarian cancer tumor burden using Magnetic Particle Imaging and non-dilutive cell labelingR01EB019458 · NIBIB · UNIVERSITY OF CALIFORNIA BERKELEY · PI BELL, CALEB B., CONOLLY, STEVEN M · 2015 to 2018
$1.9M
NIBIB NIH HHS R01 EB019458NIBIB NIH HHS R01 EB024578
6 · The paper itself

Abstract

Magnetic fluid hyperthermia (MFH) treatment makes use of a suspension of superparamagnetic iron oxide nanoparticles, administered systemically or locally, in combination with an externally applied alternating magnetic field, to ablate target tissue by generating heat through a process called induction. The heat generated above the mammalian euthermic temperature of 37°C induces apoptotic cell death and/or enhances the susceptibility of the target tissue to other therapies such as radiation and chemotherapy. While most hyperthermia techniques currently in development are targeted towards cancer treatment, hyperthermia is also used to treat restenosis, to remove plaques, to ablate nerves and to alleviate pain by increasing regional blood flow. While RF hyperthermia can be directed invasively towards the site of treatment, non-invasive localization of heat through induction is challenging. In this review, we discuss recent progress in the field of RF magnetic fluid hyperthermia and introduce a new diagnostic imaging modality called magnetic particle imaging that allows for a focused theranostic approach encompassing treatment planning, treatment monitoring and spatially localized inductive heating.

Indexed as

AnimalsBrain NeoplasmsCoated Materials, BiocompatibleDiagnostic ImagingEquipment DesignFerric CompoundsForecastingHumansHyperthermia, InducedMagnetic Iron Oxide NanoparticlesMagneticsMaleMicePilot ProjectsProstatic NeoplasmsRadiofrequency TherapyCoated Materials, BiocompatibleFerric Compoundsferric oxidehyperthermiain vivo Trackingmagnetic fluid hyperthermiaMagnetic NanoparticlesMagnetic Particle ImagingRF hyperthermiaRF treatment monitoringRF treatment planningSuperparamagnetic Iron Oxide NanoparticlesTheranostics

Identifiers

PMID32194849
PMCPMC7053197
OpenAlexW3006424074

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.