Evidence map›Paper›PMID 32194845›Full record

ArticleTheranostics2020

Integrin αvβ6-specific therapy for pancreatic cancer developed from foot-and-mouth-disease virus.

Kate M Moore, Ami Desai, Bea de Luxán Delgado, Sara Maria David Trabulo, Claire Reader, Nicholas F Brown, Elizabeth R Murray, Adam Brentnall, Philip Howard, Luke Masterson and 4 more

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 46 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. PET/CT imaging of esophageal cancer targeting tumor cell specific αvβ6-integrin expression.European journal of nuclear medicine and molecular imaging · 2025
    Article
  5. Peptide-Drug Conjugates: A New Hope for Cancer.Journal of peptide science : an official publication of the European Peptide Society · 2025
    Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Integrins in cancer stem cells.Frontiers in cell and developmental biology · 2024
    Review
  11. Article
  12. Review
  13. Small extracellular vesicle-mediatedCancer biology & therapy · 2022
    Article
  14. Article
  15. Integrin Alpha v Beta 6 (αvβ6) and Its Implications in Cancer Treatment.International journal of molecular sciences · 2022
    Review
  16. Article
  17. Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Kate M MooreBarts Cancer Institute, Queen Mary University of London, John Vane Science Centre, Charterhouse Square, London EC1M 6BQ, UK.
Ami DesaiBarts Cancer Institute, Queen Mary University of London, John Vane Science Centre, Charterhouse Square, London EC1M 6BQ, UK.
Bea de Luxán DelgadoBarts Cancer Institute, Queen Mary University of London, John Vane Science Centre, Charterhouse Square, London EC1M 6BQ, UK.
Sara Maria David TrabuloBarts Cancer Institute, Queen Mary University of London, John Vane Science Centre, Charterhouse Square, London EC1M 6BQ, UK.
Claire ReaderBarts Cancer Institute, Queen Mary University of London, John Vane Science Centre, Charterhouse Square, London EC1M 6BQ, UK.
Nicholas F BrownBarts Cancer Institute, Queen Mary University of London, John Vane Science Centre, Charterhouse Square, London EC1M 6BQ, UK.
Elizabeth R MurrayBarts Cancer Institute, Queen Mary University of London, John Vane Science Centre, Charterhouse Square, London EC1M 6BQ, UK.
Adam BrentnallCancer Research UK Centre for Epidemiology, Mathematics and Statistics, Wolfson Institute of Preventative Medicine, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK.
Philip HowardSpirogen, QMB Innovation Centre, 42 New Road, London E1 2AX, UK.
Luke MastersonSpirogen, QMB Innovation Centre, 42 New Road, London E1 2AX, UK.
Francesca ZammarchiADC Therapeutics (UK) Ltd, QMB Innovation Centre, 42 New Road, London E1 2AX, UK.
John A HartleyCancer Research UK Drug-DNA Interactions Research Group, University College London Cancer Institute, 72 Huntley Street, London WC1E 6BT, U.K.
Patrick H van BerkelADC Therapeutics (UK) Ltd, QMB Innovation Centre, 42 New Road, London E1 2AX, UK.
John F MarshallBarts Cancer Institute, Queen Mary University of London, John Vane Science Centre, Charterhouse Square, London EC1M 6BQ, UK.
Queen Mary University of London · GBSpirogen (United Kingdom) · GB

Funding

Cancer Research UK 16880Cancer Research UK 21624
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsAntigens, NeoplasmApoptosisBenzodiazepinesCapsid ProteinsCarcinoma, Pancreatic DuctalCell Line, TumorDNA DamageFemaleHumansIntegrinsMiceMice, KnockoutPancreatic NeoplasmsPeptidesPyrrolesAntigens, NeoplasmBenzodiazepinesCapsid Proteinsintegrin alphavbeta6IntegrinsPeptidesPyrrolespyrrolo(2,1-c)(1,4)benzodiazepineVP1 protein, Foot-and-mouth disease virusintegrinPDACpeptide-drug conjugateαvβ6

Identifiers

PMID32194845
PMCPMC7053198
OpenAlexW3006102983

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.