Evidence map›Paper›PMID 32194844›Full record

ArticleTheranostics2020

One-pot synthesis of a microporous organosilica-coated cisplatin nanoplatform for HIF-1-targeted combination cancer therapy.

Xiaojuan Zhang, Chuanchuan He, Xiaoguang Liu, Yan Chen, Pengxuan Zhao, Chen Chen, Ruicong Yan, Minsi Li, Ting Fan, Bouhari Altine and 5 more

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 43 citations in OpenAlex.

  1. Charge-convertible MnOiScience · 2026
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  12. Sirtuins and Hypoxia in EMT Control.Pharmaceuticals (Basel, Switzerland) · 2022
    Review
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  14. Article
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  16. A smart OActa pharmaceutica Sinica. B · 2021
    Article
  17. Review
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 2 countries.

Xiaojuan ZhangSchool of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
Chuanchuan HeSchool of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
Xiaoguang LiuSchool of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
Yan ChenSchool of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
Pengxuan ZhaoSchool of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
Chen ChenSchool of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
Ruicong YanSchool of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
Minsi LiSchool of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
Ting FanSchool of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
Bouhari AltineDepartment of Nuclear Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Tan YangSchool of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
Yao LuSchool of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
Robert J LeeDivision of Pharmaceutics and Pharmacology, The Ohio State University, Columbus, OH 43210, USA.
Yongkang GaiDepartment of Nuclear Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Guangya XiangSchool of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
Huazhong University of Science and Technology · CNThe Ohio State University · USUnion Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nanoparticle formulations have proven effective for cisplatin delivery. However, the development of a versatile nanoplatform for cisplatin-based combination cancer therapies still remains a great challenge.

Indexed as

A549 CellsAcriflavineAnimalsAntineoplastic AgentsCisplatinDrug CarriersDrug Therapy, CombinationHumansHypoxia-Inducible Factor 1, alpha SubunitMiceNanoparticlesNeoplasmsSilicon DioxideAcriflavineAntineoplastic AgentsCisplatinDrug CarriersHif1a protein, mouseHypoxia-Inducible Factor 1, alpha SubunitSilicon Dioxideacriflavinecisplatincombination therapyHIF-1nanoparticle

Identifiers

PMID32194844
PMCPMC7053205
OpenAlexW3006400217

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.