Evidence map›Paper›PMID 32194839›Full record

ArticleTheranostics2020

Localized anesthesia of a specific brain region using ultrasound-responsive barbiturate nanodroplets.

Harriet Lea-Banks, Meaghan A O'Reilly, Clement Hamani, Kullervo Hynynen

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 52 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Overview of Therapeutic Ultrasound Applications and Safety Considerations: 2024 Update.Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2025
    Review
  5. Review
  6. Remotely controlled drug release in deep brain regions of non-human primates.Journal of controlled release : official journal of the Controlled Release Society · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Acoustomechanically activatable liposomes for ultrasonic drug uncaging.bioRxiv : the preprint server for biology · 2023
    Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Emerging Anesthetic Nanomedicines: Current State and Challenges.International journal of nanomedicine · 2023
    Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Harriet Lea-BanksPhysical Sciences Platform, Sunnybrook Research Institute, Toronto, Canada.
Meaghan A O'ReillyPhysical Sciences Platform, Sunnybrook Research Institute, Toronto, Canada.
Clement HamaniDivision of Neurosurgery, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Canada.
Kullervo HynynenPhysical Sciences Platform, Sunnybrook Research Institute, Toronto, Canada.
University of Toronto · CASunnybrook Health Science Centre · CA

Funding

Ultrasound Therapy Delivery Through Intact SkullR01EB003268 · NIBIB · SUNNYBROOK & WOMEN'S COLL HLTH SCIS CTR · PI HYNYNEN, KULLERVO · 2003 to 2020
$8.2M
NIBIB NIH HHS R01 EB003268
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

UltrasonographyAnesthesiaAnimalsDrug Delivery SystemsFluorocarbonsHypnotics and SedativesMaleMicrobubblesNanoparticlesPentobarbitalRatsRats, Sprague-DawleyFluorocarbonsHypnotics and SedativesPentobarbitalperfluorobutaneperflutrenfocused ultrasoundphase-change emulsiontriggered drug delivery

Identifiers

PMID32194839
PMCPMC7052887
OpenAlexW3006339932

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.