Evidence map›Paper›PMID 32194836›Full record

ArticleTheranostics2020

Dysbiosis of intestinal microbiota mediates tubulointerstitial injury in diabetic nephropathy via the disruption of cholesterol homeostasis.

Ze Bo Hu, Jian Lu, Pei Pei Chen, Chen Chen Lu, Jia Xiu Zhang, Xue Qi Li, Ben Yin Yuan, Si Jia Huang, Xiong Zhong Ruan, Bi Cheng Liu and 1 more

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
70citing papers in PubMed, 3 pooled it
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

70 citing papers in PubMed, 3 syntheses or guidelines pooled it, 100 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Review
  5. Microbiota-gut-kidney axis in health and renal disease.International journal of biological sciences · 2026
    Review
  6. Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Review
  18. Article
  19. Gut-X axis.iMeta · 2025
    Review
  20. Article

10 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Ze Bo HuInstitute of Nephrology, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, 210009, China.
Jian LuInstitute of Nephrology, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, 210009, China.
Pei Pei ChenInstitute of Nephrology, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, 210009, China.
Chen Chen LuInstitute of Nephrology, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, 210009, China.
Jia Xiu ZhangInstitute of Nephrology, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, 210009, China.
Xue Qi LiInstitute of Nephrology, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, 210009, China.
Ben Yin YuanInstitute of Nephrology, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, 210009, China.
Si Jia HuangInstitute of Nephrology, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, 210009, China.
Xiong Zhong RuanCentre for Nephrology, University College London (UCL) Medical School, Royal Free Campus, UK.
Bi Cheng LiuInstitute of Nephrology, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, 210009, China.
Kun Ling MaInstitute of Nephrology, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, 210009, China.
Zhongda Hospital Southeast University · CNThe Royal Free Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Diabetic NephropathiesDysbiosisGastrointestinal MicrobiomeNephritis, InterstitialAcetatesAnimalsCell LineCholesterolHomeostasisHumansMaleRatsRats, Sprague-DawleyReceptors, G-Protein-CoupledAcetatesCholesterolFfar2 protein, ratReceptors, G-Protein-Coupledacetatecholesterol homeostasisdiabetic nephropathygut microbiotatubulointerstitial injury

Identifiers

PMID32194836
PMCPMC7052905
OpenAlexW3005831371

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.