Evidence map›Paper›PMID 32194821›Full record

ArticleTheranostics2020

Real-time colorectal cancer diagnosis using PR-OCT with deep learning.

Yifeng Zeng, Shiqi Xu, William C Chapman, Shuying Li, Zahra Alipour, Heba Abdelal, Deyali Chatterjee, Matthew Mutch, Quing Zhu

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 1 synthesis or guideline pooled it, 60 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Yifeng ZengDepartment of Biomedical Engineering, Washington University in St. Louis.
Shiqi XuDepartment of Electrical & System Engineering, Washington University in St. Louis.
William C ChapmanDepartment of Surgery, Section of Colon and Rectal Surgery, Washington University School of Medicine.
Shuying LiDepartment of Biomedical Engineering, Washington University in St. Louis.
Zahra AlipourDepartment of Pathology and Immunology, Washington University School of Medicine.
Heba AbdelalDepartment of Pathology and Immunology, Washington University School of Medicine.
Deyali ChatterjeeDepartment of Pathology and Immunology, Washington University School of Medicine.
Matthew MutchDepartment of Surgery, Section of Colon and Rectal Surgery, Washington University School of Medicine.
Quing ZhuDepartment of Biomedical Engineering, Washington University in St. Louis.
Washington University in St. Louis · USColon and Rectal Surgery Associates · US

Funding

SURGICAL ONCOLOGY TRAINING GRANTT32CA009621 · NCI · WASHINGTON UNIVERSITY · PI TIMOTHY J. EBERLEIN, William E. Gillanders · 1988 to 2026
$12.9M
Near Infrared Diffused Light Imaging with Ultrasound Guidance: Predicting Neoadjuvant Chemotherapy ResponseR01EB002136 · NIBIB · WASHINGTON UNIVERSITY · PI ZHU, QUING · 2003 to 2016
$3.4M
Improving diagnostic US for reduction of benign breast biopsies using US-guided Optical TomographyR01CA228047 · NCI · WASHINGTON UNIVERSITY · PI POPLACK, STEVEN, ZHU, QUING · 2019 to 2023
$1.9M
Co-registered photoacoustic and ultrasound imaging for non-invasive ovarian canR01CA151570 · NCI · WASHINGTON UNIVERSITY · PI BREWER, MOLLY A., ZHU, QUING · 2011 to 2015
$1.6M
NCI NIH HHS R01 CA151570NCI NIH HHS R01 CA228047NCI NIH HHS T32 CA009621NIBIB NIH HHS R01 EB002136
6 · The paper itself

Abstract

Prior reports have shown optical coherence tomography (OCT) can differentiate normal colonic mucosa from neoplasia, potentially offering an alternative technique to endoscopic biopsy - the current gold-standard colorectal cancer screening and surveillance modality. To help clinical translation limited by processing the large volume of generated data, we designed a deep learning-based pattern recognition (PR) OCT system that automates image processing and provides accurate diagnosis potentially in real-time.

Indexed as

Deep LearningAgedAged, 80 and overColonColorectal NeoplasmsDiagnosis, Computer-AssistedHumansImage Processing, Computer-AssistedMiddle AgedTomography, Optical Coherencecolorectal cancerdeep learningoptical biopsyoptical coherence tomography (OCT)

Identifiers

PMID32194821
PMCPMC7052898
OpenAlexW3006670569

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.