Evidence map›Paper›PMID 32194743›Full record

ArticleOncology letters2020

Expression levels and associations of five long non-coding RNAs in gastric cancer and their clinical significance.

Helen Barong Binang, Yun-Shan Wang, Marlvin Anemey Tewara, Lutao Du, Shuang Shi, Ning Li, Ariston Gabriel Abakundana Nsenga, Chuanxin Wang

Open access · diamondAbstract read
In one paragraph

Article in Oncology letters, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Helen Barong BinangDepartment of Clinical Laboratory, The Second Hospital of Shandong University, Jinan, Shandong 250033, P.R. China.
Yun-Shan WangDepartment of Clinical Laboratory, The Second Hospital of Shandong University, Jinan, Shandong 250033, P.R. China.
Marlvin Anemey TewaraDepartment of Biostatistics, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250012, P.R. China.
Lutao DuDepartment of Clinical Laboratory, The Second Hospital of Shandong University, Jinan, Shandong 250033, P.R. China.
Shuang ShiDepartment of Clinical Laboratory, The Second Hospital of Shandong University, Jinan, Shandong 250033, P.R. China.
Ning LiDepartment of Clinical Laboratory, The Second Hospital of Shandong University, Jinan, Shandong 250033, P.R. China.
Ariston Gabriel Abakundana NsengaDepartment of Clinical Laboratory, The Second Hospital of Shandong University, Jinan, Shandong 250033, P.R. China.
Chuanxin WangDepartment of Clinical Laboratory, The Second Hospital of Shandong University, Jinan, Shandong 250033, P.R. China.
Second Hospital of Shandong University · CNShandong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gastric cancer (GC) is a type of cancer that is commonly diagnosed worldwide due to a lack of early diagnostic, prognostic and therapeutic targets for this disease. The aim of the present study was to examine the expression levels of five long non-coding RNAs, namely PTPRG antisense RNA 1 (PTPRG-AS1), forkhead box P4 antisense RNA 1 (FOXP4-AS1), bladder cancer-associated transcript 2 (BLACAT2), ZXF2 and upregulated in colorectal cancer (UCC), to study their associations with patient characteristics and assess their prognostic efficacy, in order to determine the possibility of their application as GC biomarkers. The expression levels of long non-coding RNAs (lncRNAs) were determined by reverse transcription-quantitative PCR analysis of 61 pairs of GC tissues and adjacent healthy gastric mucosa tissues and GC cell lines. The Chi-square test was conducted to assess the associations of lncRNA expression levels with clinical characteristics of patients. The effect of UCC on GC cell proliferation was determined using

Indexed as

cell proliferationdisease-free survivalgastric cancerlong non-coding RNAsoverall survivalrelative expression

Identifiers

PMID32194743
PMCPMC7039045
OpenAlexW3000034647

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.