Evidence map›Paper›PMID 32194741›Full record

ArticleOncology letters2020

Expression of molecules of the Wnt pathway and of E-cadherin in the etiopathogenesis of human thymomas.

Prokop Vodicka, Lenka Krskova, Igor Odintsov, Ludmila Krizova, Eva Sedlackova, Jan Schutzner, Josef Zamecnik

Open access · diamondAbstract read
In one paragraph

Article in Oncology letters, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Oncology Clinical Trials Targeting Members of the Cadherin Superfamily: A Review.Journal of immunotherapy and precision oncology · 2025
    Review
  2. The Molecular Landscape of Thymic Epithelial Tumors: A Comprehensive Review.International journal of molecular sciences · 2024
    Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Prokop VodickaDepartment of Pathology and Molecular Medicine, Second Faculty of Medicine, Charles University and Motol University Hospital, Prague 150 06, Czech Republic.
Lenka KrskovaDepartment of Pathology and Molecular Medicine, Second Faculty of Medicine, Charles University and Motol University Hospital, Prague 150 06, Czech Republic.
Igor OdintsovDepartment of Pathology and Molecular Medicine, Second Faculty of Medicine, Charles University and Motol University Hospital, Prague 150 06, Czech Republic.
Ludmila KrizovaDepartment of Oncology, First Faculty of Medicine, Charles University and General University Hospital, Prague 128 08, Czech Republic.
Eva SedlackovaDepartment of Oncology, First Faculty of Medicine, Charles University and General University Hospital, Prague 128 08, Czech Republic.
Jan SchutznerThird Department of Surgery, First Faculty of Medicine, Charles University and Motol University Hospital, Prague 150 06, Czech Republic.
Josef ZamecnikDepartment of Pathology and Molecular Medicine, Second Faculty of Medicine, Charles University and Motol University Hospital, Prague 150 06, Czech Republic.
Charles University · CZUniversity Hospital in Motol · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The molecular pathogenesis of thymoma remains largely unknown. It has been recently demonstrated, that activation of Wnt signaling pathway leads to increased incidence of thymoma in murine models. The present study investigated the activation of molecules of the Wnt signaling pathway in human thymoma. A total of 112 thymoma cases with complete clinical and follow-up data and 8 controls were included in the present study. Patients with thymoma and controls were examined immunohistochemically for β-catenin and E-cadherin. The mRNA expression levels of

Indexed as

axin2E-cadherinthymomaWntβ-catenin

Identifiers

PMID32194741
PMCPMC7039126
OpenAlexW3002792872

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.