Evidence map›Paper›PMID 32194725›Full record

ArticleOncology letters2020

miR-202 functions as a tumor suppressor in hepatocellular carcinoma by targeting HK2.

Jiangang Wang, Jili Chen, Fang Sun, Zhiwei Wang, Wenfang Xu, Yafeng Yu, Feng Ding, Huajiang Shen

Open access · diamondAbstract read
In one paragraph

Article in Oncology letters, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Review
  6. Review
  7. The microRNA-202 as a Diagnostic Biomarker and a Potential Tumor Suppressor.International journal of molecular sciences · 2022
    Review
  8. Review
  9. Article
  10. OncoTargets and therapy · 2021
    Article
  11. Article
  12. Article
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Jiangang WangDepartment of Liver Disease, Affiliated Hospital of Shaoxing University, Shaoxing, Zhejiang 312000, P.R. China.
Jili ChenDepartment of Liver Disease, Affiliated Hospital of Shaoxing University, Shaoxing, Zhejiang 312000, P.R. China.
Fang SunDepartment of Liver Disease, Affiliated Hospital of Shaoxing University, Shaoxing, Zhejiang 312000, P.R. China.
Zhiwei WangDepartment of Liver Disease, Affiliated Hospital of Shaoxing University, Shaoxing, Zhejiang 312000, P.R. China.
Wenfang XuDepartment of Liver Disease, Affiliated Hospital of Shaoxing University, Shaoxing, Zhejiang 312000, P.R. China.
Yafeng YuDepartment of Liver Disease, Affiliated Hospital of Shaoxing University, Shaoxing, Zhejiang 312000, P.R. China.
Feng DingDepartment of Liver Disease, Affiliated Hospital of Shaoxing University, Shaoxing, Zhejiang 312000, P.R. China.
Huajiang ShenDepartment of Liver Disease, Affiliated Hospital of Shaoxing University, Shaoxing, Zhejiang 312000, P.R. China.
Shaoxing University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent evidence has suggested that microRNAs (miRNAs) can participate in metabolic reprogramming. Additionally, aerobic glycolysis is associated with tumor progression in hepatocellular carcinoma (HCC). In the present study, miRNA (miR)-202 expression levels were found to be significantly lower in HCC tissues compared with the corresponding adjacent non-cancerous tissue samples using reverse transcription-quantitative PCR analysis in 56 patients with HCC. Lower miR-202 expression levels were identified to be associated with tumor size, vascular invasion, Tumor, Node and Metastasis stages and poor overall survival rates in patients with HCC.

Indexed as

cell proliferationglycolysishepatocellular carcinomahexokinase 2microRNA-202

Identifiers

PMID32194725
PMCPMC7039053
OpenAlexW3002717619

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.