Evidence map›Paper›PMID 32194559›Full record

ArticleFrontiers in immunology2020

Defective Interferon Gamma Production by Tumor-Specific CD8

Megat Abd Hamid, Xuan Yao, Craig Waugh, Samara Rosendo-Machado, Chris Li, Timothy Rostron, John Frankland, Yanchun Peng, Tao Dong

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. CD8Nature reviews. Immunology · 2022
    Review
  8. Review
  9. Review
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Megat Abd HamidChinese Academy of Medical Sciences (CAMS) Oxford Institute, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.
Xuan YaoChinese Academy of Medical Sciences (CAMS) Oxford Institute, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.
Craig WaughFlow Cytometry Facility, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom.
Samara Rosendo-MachadoMedical Research Council (MRC) Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom.
Chris LiMedical Research Council (MRC) Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom.
Timothy RostronSequencing Facility, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom.
John FranklandSequencing Facility, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom.
Yanchun PengChinese Academy of Medical Sciences (CAMS) Oxford Institute, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.
Tao DongChinese Academy of Medical Sciences (CAMS) Oxford Institute, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.
MRC Weatherall Institute of Molecular Medicine · GBAcademy of Medical Sciences · GBChinese Academy of Medical Sciences & Peking Union Medical College · CNMedical Research Council · GBUniversity of Oxford · GB

Funding

Medical Research Council MR/L018942/1
6 · The paper itself

Abstract

Interferon gamma (IFNγ) supports effector responses of CD8

Indexed as

DNA MethylationAntigens, NeoplasmCD8-Positive T-LymphocytesCpG IslandsHumansInterferon-gammaPromoter Regions, GeneticAntigens, NeoplasmInterferon-gammaCD8+ T cellsinterferon gammamethylationmRNApromoterresponse

Identifiers

PMID32194559
PMCPMC7066077
OpenAlexW3009095825

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.