Evidence map›Paper›PMID 32194542›Full record

ArticleFrontiers in immunology2020

FTY720 Exerts Anti-Glioma Effects by Regulating the Glioma Microenvironment Through Increased CXCR4 Internalization by Glioma-Associated Microglia.

Xu-Dong Guo, Juan Ji, Teng-Fei Xue, Yu-Qin Sun, Ruo-Bing Guo, Hong Cheng, Xiu-Lan Sun

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 30 citations in OpenAlex.

  1. Targeting PP2A in cancer: an underrated option.Journal of experimental & clinical cancer research : CR · 2025
    Review
  2. Review
  3. Article
  4. Regulation of CXCR4 function by S1PCell communication and signaling : CCS · 2025
    Article
  5. Article
  6. Pharmacological Effects of FTY720 and its Derivatives.Current topics in medicinal chemistry · 2024
    Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Microglia and Brain Macrophages as Drivers of Glioma Progression.International journal of molecular sciences · 2022
    Review
  12. The Role of NRF2/KEAP1 Pathway in Glioblastoma: Pharmacological Implications.Medical oncology (Northwood, London, England) · 2022
    Review
  13. Article
  14. Article
  15. Macrophages/Microglia in the Glioblastoma Tumor Microenvironment.International journal of molecular sciences · 2021
    Review
  16. Article
  17. Article
  18. Review
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Xu-Dong GuoNeuroprotective Drug Discovery Key Laboratory of Nanjing Medical University, Jiangsu Key Laboratory of Neurodegeneration, Nanjing Medical University, Nanjing, China.
Juan JiNeuroprotective Drug Discovery Key Laboratory of Nanjing Medical University, Jiangsu Key Laboratory of Neurodegeneration, Nanjing Medical University, Nanjing, China.
Teng-Fei XueNeuroprotective Drug Discovery Key Laboratory of Nanjing Medical University, Jiangsu Key Laboratory of Neurodegeneration, Nanjing Medical University, Nanjing, China.
Yu-Qin SunNeuroprotective Drug Discovery Key Laboratory of Nanjing Medical University, Jiangsu Key Laboratory of Neurodegeneration, Nanjing Medical University, Nanjing, China.
Ruo-Bing GuoNeuroprotective Drug Discovery Key Laboratory of Nanjing Medical University, Jiangsu Key Laboratory of Neurodegeneration, Nanjing Medical University, Nanjing, China.
Hong ChengThe First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Xiu-Lan SunNeuroprotective Drug Discovery Key Laboratory of Nanjing Medical University, Jiangsu Key Laboratory of Neurodegeneration, Nanjing Medical University, Nanjing, China.
Nanjing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AllograftsAnimalsAntineoplastic AgentsCell Line, TumorCell MovementCell PolarityDisease Models, AnimalFingolimod HydrochlorideGlioblastomaMacrophagesMaleMicrogliaMitogen-Activated Protein KinasesRatsRats, Sprague-DawleyRats, WistarAntineoplastic AgentsCxcr4 protein, ratFingolimod HydrochlorideMitogen-Activated Protein KinasesReceptors, CXCR4chemoattractionFTY720glioma-associated microglia and macrophagesglioma microenvironmentpolarization

Identifiers

PMID32194542
PMCPMC7065571
OpenAlexW3009639973

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.