Evidence map›Paper›PMID 32194332›Full record

ArticleSaudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society2020

The use of quantitative analysis and Hansen solubility parameter predictions for the selection of excipients for lipid nanocarriers to be loaded with water soluble and insoluble compounds.

Pedzisai A Makoni, Janeeta Ranchhod, Kasongo WaKasongo, Sandile M Khamanga, Roderick B Walker

Abstract read
In one paragraph

Article in Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Pedzisai A MakoniDivision of Pharmaceutics, Faculty of Pharmacy, Rhodes University, 6140 Grahamstown, South Africa.
Janeeta RanchhodDivision of Pharmaceutics, Faculty of Pharmacy, Rhodes University, 6140 Grahamstown, South Africa.
Kasongo WaKasongoDivision of Pharmaceutics, Faculty of Pharmacy, Rhodes University, 6140 Grahamstown, South Africa.
Sandile M KhamangaDivision of Pharmaceutics, Faculty of Pharmacy, Rhodes University, 6140 Grahamstown, South Africa.
Roderick B WalkerDivision of Pharmaceutics, Faculty of Pharmacy, Rhodes University, 6140 Grahamstown, South Africa.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of these studies was to determine the miscibility of different API with lipid excipients to predict drug loading and encapsulation properties for the production of solid lipid nanoparticles and nanostructured lipid carriers. Five API exhibiting different physicochemical characteristics,

Indexed as

ClarithromycinDidanosineEfavirenzHansen solubility parameterLipid nanoparticles and nanocarriersMinocycline hydrochlorideMometasone furoateSolubility

Identifiers

PMID32194332
PMCPMC7078564

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.