Evidence map›Paper›PMID 32194314›Full record

ArticleEgyptian journal of occupational medicine2019

Neurobehavioral and Menstrual Disorders among Adolescent Females Environmentally Exposed to Pesticides, Menoufia Governorate, Egypt.

G M Abdel-Rasoul, E A Salem, A S Elbadry, O M Hendy, D S Rohlman, A A Abdel-Latif

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Egyptian journal of occupational medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.7field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Menstrual Cycle Patterns and Irregularities in Hired Latinx Child Farmworkers.Journal of occupational and environmental medicine · 2021
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

G M Abdel-RasoulPublic Health and Community Medicine Department, Faculty of Medicine, Menoufia University, Egypt.
E A SalemPublic Health and Community Medicine Department, Faculty of Medicine, Menoufia University, Egypt.
A S ElbadryPublic Health and Community Medicine Department, Faculty of Medicine, Menoufia University, Egypt.
O M HendyClinical Pathology Department, National Liver Institute, Menoufia University, Egypt.
D S RohlmanDepartment of Occupational and Environmental Health, College of Public Health, University of Iowa, Iowa City, USA.
A A Abdel-LatifPublic Health and Community Medicine Department, Faculty of Medicine, Menoufia University, Egypt.
Menoufia University · EGUniversity of Iowa · US

Funding

Pulmonary Toxicology Facility CoreP30ES005605 · NIEHS · UNIVERSITY OF IOWA · PI HANS-JOACHIM LEHMLER · 1990 to 2026
$40.5M
Vulnerability of the Adolescent Brain to Organophosphorus PesticidesR01ES022163 · NIEHS · UNIVERSITY OF IOWA · PI ROHLMAN, DIANE S · 2013 to 2018
$2.7M
NIEHS NIH HHS P30 ES005605NIEHS NIH HHS R01 ES022163
6 · The paper itself

Abstract

backgroundAdolescent females living in agricultural areas where crops are routinely sprayed by pesticides are expected to be environmentally exposed to pesticides' health hazards partially as those occupationally exposed.

objectiveto assess menstrual and neurobehavioral disorders among adolescent females environmentally exposed to pesticides.

methodsThis was a cross-sectional study conducted on 100 pesticide exposed adolescent females who had one or more of family members are pesticides' seasonal applicators and 50 non- exposed adolescent females matched for age and education, served as controls at Menoufia governorate, Egypt during the period of pesticide application season of cotton crop from the first days of May to the end of September 2017. A self-administered and a series of neurobehavioral tests were administered and serum Acetylcholinesterase (AChE) activity was assessed.

resultsA significant lower AChE activity levels were found in the exposed group than controls (Mean±SD=238.49± 23.83 vs 303.35±78.54 IU/L; respectively). There were significant higher mean scores of trail making test (parts 1 and 2) and significant lower mean scores of (similarities test, Benton visual retention test, block design test, Santa Ana dexterity test (dominant and non-dominant hands) and Beery visuo-motor imitation test in the exposed group than the controls (P<0.05). Also, the exposed group reported more prevalent irregular menstrual cycle (26.8%) and intermenstrual bleeding (28.2%) compared to the control participants (8.1% and 8.1%; respectively).

conclusionAdolescent females living in agricultural areas and from families whose one or more members are pesticides' applicators have significantly lower neurobehavioral performance, report more prevalent menstrual irregularities and have lower levels of serum AChE compared to a control group. The neurobehavioral deficits demonstrated a dose-response relationship AChE levels in the exposed participants. This necessitates the need for implementation of health education programs to prevent or reduce health effects associated with pesticide exposure to adolescent females.

Indexed as

AChEAdolescent femalesEnvironmental Pesticides’ ExposureMenstrual and Neurobehavioral Disorders

Identifiers

PMID32194314
PMCPMC7081947
OpenAlexW2974432812

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.