Evidence map›Paper›PMID 32194301›Full record

ArticleChinese journal of cancer research = Chung-kuo yen cheng yen chiu2020

Updates on larynx cancer epidemiology.

Riccardo Nocini, Gabriele Molteni, Camilla Mattiuzzi, Giuseppe Lippi

Registry-linked trialAbstract read
In one paragraph

Article in Chinese journal of cancer research = Chung-kuo yen cheng yen chiu, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05832593 (Immunohistochemical Expression of Excision Repair Cross Complementation Group 1), which is not on this map. Cited by 139 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
139citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05832593 unknown statusnot on this mapstarted 2023, after this paper: background citation

Immunohistochemical Expression of Excision Repair Cross Complementation Group 1 (ERCC1) in Laryngeal Squamous Cell Carcinoma and Its Correlation With Response to Radiotherapy.

TypeobservationalSponsorAssiut UniversityRan2023 to 2025Enrolled52ConditionsLaryngeal Squamous Cell CarcinomaArmsImmunohistochemistry
3 · Its place in the literature

Who cites it

139 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Stapler versus manual closure for pharyngeal repair after total laryngectomy: a systematic review and meta-analysis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Pooled it
  2. Pooled it
  3. Pooled it
  4. Value and role of surgical margins in transoral laser microsurgery of the larynx, literature review and clinical considerations.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024
    Pooled it
  5. The application of radiomics in laryngeal cancer.The British journal of radiology · 2021
    Pooled it
  6. Laryngeal Cancer Survival in Northern United Kingdom: A Multi-Centre Retrospective Observational Study.Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery · 2026
    Observational
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  8. Risk factors for thyroid gland invasion in advanced laryngeal cancer: implications for selective thyroidectomy.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
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  11. Association of preoperative hemoglobin levels with the risk of pharyngocutaneous fistula after surgery for laryngeal and hypopharyngeal squamous cell carcinoma.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Article
  12. Impact of implemented strategies on survival and complications in laryngectomized patients: a retrospective cohort study from an oncology reference center.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
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  15. Treatment regimens for laryngeal and hypopharyngeal squamous cell carcinoma: a "real life" multicenter study of 2307 patients.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
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  17. Integrative analysis identifiedTranslational cancer research · 2025
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79 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Riccardo NociniSection of Ear Nose and Throat (ENT), Department of Surgical Sciences, Dentistry, Gynecology and Pediatrics, University of Verona, Verona 37134, Italy.
Gabriele MolteniSection of Ear Nose and Throat (ENT), Department of Surgical Sciences, Dentistry, Gynecology and Pediatrics, University of Verona, Verona 37134, Italy.
Camilla MattiuzziService of Clinical Governance, Provincial Agency for Social and Sanitary Services, Trento 38123, Italy.
Giuseppe LippiSection of Clinical Biochemistry, Department of Neuroscience, Biomedicine and Movement, University of Verona, Verona 37134, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveLaryngeal cancer is an important oncologic entity, whose prognosis depends on establishing appropriate preventive and diagnostic measures, especially in populations at higher risk.

methodsEpidemiologic information including worldwide incidence, prevalence, burden of health loss (disability-adjusted life year; DALYs) and mortality of larynx cancer was obtained from the Global Health Data Exchange (GHDx) database.

resultsThe current incidence, prevalence and mortality of laryngeal cancer are estimated at 2.76 cases/year per 100,000 inhabitants, 14.33 cases/year per 100,000 inhabitants and 1.66 deaths/year per 100,000 inhabitants, respectively, averaging 3.28 million DALYs each year. Incidence and prevalence have increased by 12% and 24%, respectively during the past 3 decades, whilst mortality has declined by around 5%. The epidemiologic burden of this malignancy is approximately 5-fold higher in males and increases in parallel with ageing, peaking after 65 years of age. Both incidence and mortality rates are higher in Europe and lower in Africa, but the ratio between deaths and incidence is the highest in Africa. Incidence has gradually declined in Europe during the past 3 decades, whilst it has increased in South-East Asia and Western Pacific. Cigarette smoking and alcohol abuse contribute for about 90% of overall worldwide mortality for laryngeal cancer.

conclusionsLaryngeal cancer still poses a high clinical and societal burden, with an escalating temporal trend not expected to reverse soon.

Indexed as

epidemiologylaryngeal cancerLarynxlarynx cancermortality

Identifiers

PMID32194301
PMCPMC7072014

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.