ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2020
The WHOQOL-BREF: a modern psychometric evaluation of its internal construct validity in people with multiple sclerosis.
Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Development and Validation of the WAI-Tele-Reha-G: A Measure of Therapeutic Alliance in Telerehabilitation.Physiotherapy research international : the journal for researchers and clinicians in physical therapy · 2026Article
- Impact of hearing aid usage on the quality of life of the older adult in KwaZulu-Natal.The South African journal of communication disorders = Die Suid-Afrikaanse tydskrif vir Kommunikasieafwykings · 2026Article
- Occupational Performance and Quality of Life in Individuals With Cardiovascular Conditions: A Cross-Sectional Study.Occupational therapy international · 2026Article
- Impact of Whole-Body Cryotherapy on Pain, Sleep Quality, Functional Status, and Quality of Life in Multiple Sclerosis: A Comparative Study with Follow-Up.Journal of personalized medicine · 2025Article
- German translation, cultural adaptation for Austria, and validation of the Neurological Sleep Index-Multiple Sclerosis.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2024Article
- Modern psychometric evaluation of Thai WHOQOL-BREF and its shorter versions in patients undergoing warfarin in Thailand: Rasch analysis.Scientific reports · 2024Article
- Quality of Life Assessment Using the WHOQOL-BREF Survey in Hospitalized Patients with Alcohol Use Disorder from Romania.Diseases (Basel, Switzerland) · 2024Article
- Correlates and trajectories of relapses in relapsing-remitting multiple sclerosis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024Article
- The Association of Health Locus of Control with Clinical and Psychosocial Aspects of Living with Multiple Sclerosis.Journal of clinical psychology in medical settings · 2023Article
- Assessment of the Impact of Lower Urinary Tract Dysfunction on Quality of Life in Multiple Sclerosis Patients in Saudi Arabia-A Cross-Sectional Study.Healthcare (Basel, Switzerland) · 2023Article
- Psychometric evaluation of the Positive Mental Health (PMH) scale using item response theory.BMC psychiatry · 2022Article
- An item analysis according to the Rasch model of the German 12-item WHO Disability Assessment Schedule (WHODAS 2.0).Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2021Article
- Measurement properties of the Boston Carpal Tunnel Questionnaire in subjects with neurophysiological confirmation of carpal tunnel syndrome: a Rasch analysis perspective.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2021Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
purposeSymptoms of Multiple Sclerosis (MS) differentially impact upon quality of life (QoL) and a comprehensive measure is required for use in observational and interventional studies. This study examines the abbreviated World Health Organisation Quality of Life tool (WHOQOL-BREF) which was designed to be used as a broad measure of QoL across different cultures and diseases.
methodsData were collected from 3186 subjects as part of the TONiC study in MS and was examined with a systematic, iterative approach using Rasch analysis to investigate the internal construct validity of the WHOQOL-BREF.
resultsMean age was 49.8 years (SD 11.8), disease duration was 11.2 years (SD 9.6) and 73.2% were female. Subjects represented all stages of MS with EDSS scores of 0-4, 4.5-6.5, 7-7.5 and ≥ 8 seen in 49.8%, 38.5%, 6.8% and 4.9% of patients, respectively. Using a super-item approach, it was possible to demonstrate fit to the assumptions of the Rasch model for 3 of the 4 domains of the WHOQOL-BREF (physical, psychological and environment) as well as a broad 24-item total score. In addition, item subsets derived from the stem of each question were shown to function as novel scales measuring impact and life satisfaction. We have provided transformation tables from ordinal raw scores to interval scales where data are complete.
conclusionsThe validation of multiple conceptual frameworks validates the WHOQOL-BREF as a powerful and flexible end-point for use in clinical trials and in testing conceptual models of factors influencing QoL in MS.
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