Evidence map›Paper›PMID 32193793›Full record

ReviewCurrent osteoporosis reports2020

Kidney Disease and Bone: Changing the Way We Look at Skeletal Health.

Matthew R Allen, Elizabeth A Swallow, Corinne E Metzger

Abstract readReview
In one paragraph

Review in Current osteoporosis reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Matthew R AllenDepartment of Anatomy and Cell Biology, MS 5035, Indiana University School of Medicine, 635 Barnhill Dr, Indianapolis, IN, 46202, USA. matallen@iu.edu.
Elizabeth A SwallowDepartment of Anatomy and Cell Biology, MS 5035, Indiana University School of Medicine, 635 Barnhill Dr, Indianapolis, IN, 46202, USA.
Corinne E MetzgerDepartment of Anatomy and Cell Biology, MS 5035, Indiana University School of Medicine, 635 Barnhill Dr, Indianapolis, IN, 46202, USA.

Funding

Mechanisms of chronic kidney disease-induced cortical porosityF32DK122731 · NIDDK · INDIANA UNIVERSITY INDIANAPOLIS · PI METZGER, CORINNE · 2019 to 2021
$195k
Treating bone deterioration associated with chronic kidney diseaseI01BX003025 · VA · RLR VA MEDICAL CENTER · PI ALLEN, MATTHEW R · 2016 to 2024
–
BLRD VA I01 BX003025NIDDK NIH HHS F32 DK122731
6 · The paper itself

Abstract

purpose of reviewKidney disease imparts profound skeletal changes, and unlike many other skeletal diseases, cortical bone is predominantly impacted. Significant advances in medical imaging have led to our ability to now obtain high-resolution three-dimensional views of cortical bone. This paper overviews recent work focused on cortical bone imaging, specifically cortical porosity, in kidney disease. RECENT

findingsAlthough a number of clinical papers have used high-resolution imaging to assess cortical bone porosity, the most impactful work involves longitudinal study designs that have assessed cortical porosity changes over time. These latter studies demonstrate dramatic increases in cortical porosity in untreated individuals and a lack of clear efficacy in reversing porosity with treatment (although data are limited). Those papers providing longitudinal assessment, both clinical and pre-clinical, reveal powerful data about cortical porosity and provide a foundation upon which future studies can build.

Indexed as

Absorptiometry, PhotonAnimalsChronic Kidney Disease-Mineral and Bone DisorderCortical BoneHumansKidney Failure, ChronicPorosityRadiusRenal DialysisRenal Insufficiency, ChronicTibiaTomography, X-Ray ComputedCKD-MBDCortical boneCortical porosityHR-pQCTImaging

Identifiers

PMID32193793
PMCPMC7395483

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.