ArticleObesity surgery2020
Gut and Metabolic Hormones Changes After Endoscopic Sleeve Gastroplasty (ESG) Vs. Laparoscopic Sleeve Gastrectomy (LSG).
Article in Obesity surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 46 papers, 10 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effect of a Gas-filled Intragastric Balloon or Endoscopic Sleeve Gastroplasty for Weight Loss Compared With a Meal Replacement Weight Loss Program on Gastric Emptying, Hormonal Adaptation to Weight Loss, and Hunger
Gastric Fundus Ablation Plus Endoscopic Sleeve Gastroplasty for Weight Loss
Single-Stage Gastric Fundus Ablation and Endoscopic Sleeve Gastroplasty for Weight Loss
A Multi-site, Prospective Registry of Patients Undergoing Combined Gastric Mucosal Ablation With Endoscopic Sleeve Gastroplasty at True You Weight Loss
Who cites it
46 citing papers in PubMed, 10 syntheses or guidelines pooled it, 74 citations in OpenAlex.
- Comparing long-term weight loss and complications in endoscopic sleeve gastroplasty and laparoscopic sleeve gastrectomy: a systematic review and meta-analysis.Surgical endoscopy · 2026Pooled it
- Comparative Safety of Endoscopic Sleeve Gastroplasty Versus Laparoscopic Sleeve Gastrectomy: A Meta-Analysis of over 1.1 Million Patients.Obesity surgery · 2026Pooled it
- Endoscopic Sleeve Gastroplasty versus Laparoscopic Sleeve Gastrectomy: comparative effectiveness, safety, and metabolic outcomes: A Systematic Review and Evidence Synthesis.Obesity surgery · 2026Pooled it
- Efficacy of Endoscopic Sutured Gastroplasty on Diabetes Mellitus Type 2-A Systematic Review.Endocrinology, diabetes & metabolism · 2025Pooled it
- Endoscopic bariatric surgery for adults with overweight and obesity: a systematic review and network meta-analysis.International journal of obesity (2005) · 2025Pooled it
- IFSO Bariatric Endoscopy Committee Evidence-Based Review and Position Statement on Endoscopic Sleeve Gastroplasty for Obesity Management.Obesity surgery · 2024Pooled it
- Endoscopic therapies for patients with obesity: a systematic review and meta-analysis.Surgical endoscopy · 2023Pooled it
- Impact of Endoscopic Sleeve Gastroplasty in Non-alcoholic Fatty Liver Disease: a Systematic Review and Meta-analysis.Obesity surgery · 2023Pooled it
- Comparative Effectiveness and Safety Between Endoscopic Sleeve Gastroplasty and Laparoscopic Sleeve Gastrectomy: a Meta-analysis of 6775 Individuals with Obesity.Obesity surgery · 2022Pooled it
- Systematic Review of Innovation Reporting in Endoscopic Sleeve Gastroplasty.Obesity surgery · 2021Pooled it
- Trial
- Dumping Syndrome Following Endoscopic Sleeve Gastroplasty.ACG case reports journal · 2026Article
- A Machine-Learning Assisted Genetic Risk Score Identifies Improved Weight Loss After Endoscopic Sleeve Gastroplasty.Obesity surgery · 2026Article
- Obesity pillars roundtable: Better together - combined obesity medicine and metabolic surgery care for the treatment of obesity.Obesity pillars · 2026Article
- Endoscopic Sleeve Gastroplasty for Type 2 Diabetes: A Systematic Review and Meta-Analysis Focusing on Diabetes Remission, Glycemic Control and Body Weight Loss.Diabetes, metabolic syndrome and obesity : targets and therapy · 2026Review
- Impact of metabolic endoscopy on fibrosis regression in steatotic liver disease.World journal of hepatology · 2025Review
- Recent advances in bariatric endoscopy for obesity management: expanding the therapeutic spectrum.Singapore medical journal · 2025Article
- Gastric greater curvature plication combined with Nissen fundoplication compared to sleeve gastrectomy in patients with obesity and animal model.BMC surgery · 2025Article
- The open accordion: a novel application of endoscopic sleeve gastroplasty for the treatment of refractory gastroparesis.VideoGIE : an official video journal of the American Society for Gastrointestinal Endoscopy · 2024Article
- Fundus-to-Antrum Ratio Measured with Fluoroscopy within One Week after Endoscopic Sleeve Gastroplasty Predicts Total Body Weight Loss over Time.Journal of clinical medicine · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionESG reduces gastric lumen similar to LSG and induces significant weight loss. However, the metabolic and physiological alteration after ESG is not fully understood. We aim to study the gastrointestinal hormone changes after ESG and compared it with LSG.
methodsWe conducted a prospective pilot study comparing ESG and LSG at two centers in Spain. We administered a standard test meal after an overnight fast, and collected blood samples before and after meal. We measured the levels of ghrelin, GLP-1, peptide-YY, insulin, leptin, and adiponectin. We evaluated the hormone profile and weight changes (%TBWL) at baseline and at 6 months after the procedure.
resultsTwenty-four patients were recruited (ESG-12, LSG-12). The baseline age, sex, BMI, and fasting hormone levels were similar between the groups. At 6-month post-ESG, there was a significant decline in the leptin levels. We found a trend towards a decrease in insulin levels and improvement in insulin secretory pattern. We did not observe any change in fasting ghrelin levels, GLP-1, and PYY. At 6 months, LSG induced a significant reduction in the ghrelin, and leptin levels, and increase in peptide-YY, and adiponectin levels, respectively. A trend towards an increase in GLP-1 level was noted. However, no change in insulin was observed. LSG achieved greater %TBWL (24.4 vs. 13.3, p < 0.001) and significantly change in ghrelin, PYY, and adiponectin levels at 6 months compared to ESG.
conclusionESG induced gut hormone changes differently as compared to LSG. ESG prevented a compensatory rise in ghrelin and promoted beneficial changes in the insulin secretory pattern with weight loss.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.