Evidence map›Paper›PMID 32193623›Full record

ArticleEJNMMI research2020

HYPHYCA: a prospective study in 613 patients conducting a comprehensive analysis for predictive factors of physiological

Nicolas Aide, Laure-Eugénie Tainturier, Cathy Nganoa, Benjamin Houdu, Jennifer Kammerer, Marie-Pierre Galais, Renaud Ciappuccini, Charline Lasnon

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in EJNMMI research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03506529 (Identification of Predictive Factors for Physiological Hypermetabolism of the Anal Canal in 18F-FDG PET / CT), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03506529 completednot on this map

Identification of Predictive Factors for Physiological Hypermetabolism of the Anal Canal in 18F-FDG PET / CT

TypeobservationalSponsorCentre Francois BaclesseRan2018 to 2018Enrolled644ConditionsAnal CancerArmsquestionnary
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Value of PET imaging for radiation therapy.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Nicolas AideNormandie University, Caen, France. aide-n@chu-caen.fr.ORCID http://orcid.org/0000-0001-9207-0847
Laure-Eugénie TainturierNormandie University, Caen, France.
Cathy NganoaNuclear Medicine Department, Caen University Hospital, Avenue Côte de Nacre, 14000, Caen, France.
Benjamin HouduNuclear Medicine Department, Caen University Hospital, Avenue Côte de Nacre, 14000, Caen, France.
Jennifer KammererNormandie University, Caen, France.
Marie-Pierre GalaisDigestive Oncology Department, François Baclesse Cancer Centre, Caen, France.
Renaud CiappucciniNuclear Medicine Department, François Baclesse Cancer Centre, Caen, France.
Charline LasnonINSERM 1086 ANTICIPE, Normandie University, Caen, France.
Centre François Baclesse · FRInserm · FRNormandie Université · FRUniversité de Caen Normandie · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAnal cancer is a relatively rare tumor of which incidence increases in developed countries. MATERIALS AND

methodsOver a 2-month period, patients aged 18 years old and more, referred for

resultsSix hundred and thirteen patients were included (sex ratio F/M = 0.99) and 545 (89%) questionnaires were entirely completed. Significantly more males presented anal canal hypermetabolism (sex ratio (M/F) = 1.18 versus 0.85, p = 0.048). Moreover, patients with anal canal hypermetabolism had higher BMI (27.6 (5.7) kg/m

conclusionAccording to our study, the predictive factors of physiological anal canal hypermetabolism are high BMI, male gender, hemorrhoid history, and rectum filled with only feces. This may pave the way to a more specific interpretation of post radio-chemotherapy PET evaluations of anal canal cancer, provided that other studies are conducted in this specific population.

trial registrationThis prospective study was registered at Clinicaltrial.gov: NCT03506529; HYPHYCA on April 24, 2018.

Indexed as

18F-FDGAnal cancerPETPhysiological uptake

Identifiers

PMID32193623
PMCPMC7082447
OpenAlexW3012883831

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.