Evidence map›Paper›PMID 32193459›Full record

ArticleScientific reports2020

Adolescent overweight and obesity and the risk of papillary thyroid cancer in adulthood: a large-scale case-control study.

Kyoung-Nam Kim, Yunji Hwang, Kyu Hyung Kim, Kyu Eun Lee, Young Joo Park, Su-Jin Kim, Hyungju Kwon, Do Joon Park, BeLong Cho, Ho-Chun Choi and 2 more

Abstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
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  8. Review
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  11. Review
  12. Review
  13. Obesity and Thyroid Cancer Risk: An Update.International journal of environmental research and public health · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Kyoung-Nam Kim *Department of Preventive Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea.
Yunji Hwang *Department of Preventive Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea.
Kyu Hyung Kim *Department of Surgery, Seoul National University Bundang Hospital, Gyeonggi-do, Republic of Korea.
Kyu Eun LeeCancer Research Institute, Seoul National University, Seoul, Republic of Korea.
Young Joo ParkDepartment of Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea.ORCID http://orcid.org/0000-0002-3671-6364
Su-Jin KimCancer Research Institute, Seoul National University, Seoul, Republic of Korea.ORCID http://orcid.org/0000-0001-5511-3596
Hyungju KwonBreast and Thyroid Cancer Center, Ewha Womans University College of Medicine, Seoul, Republic of Korea.
Do Joon ParkDepartment of Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea.
BeLong ChoDepartment of Family Medicine, Center for Health Promotion and Optimal aging, Seoul National University College of Medicine and Hospital, Seoul, Republic of Korea.
Ho-Chun ChoiDepartment of Family Medicine, Healthcare System Gangnam Center, Seoul National University Hospital, Seoul, Republic of Korea.
Daehee KangDepartment of Preventive Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea.
Sue K ParkDepartment of Preventive Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea. suepark@snu.ac.kr.ORCID http://orcid.org/0000-0001-5002-9707

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to investigate the association between adolescent overweight and obesity and PTC risk in adulthood. We conducted a case-control study in the Republic of Korea with 1,549 PTC patients and 15,490 controls individually matched for age and sex. We estimated body mass index (BMI) at age 18 years from self-reported weight at this age. Compared with BMI < 23.0 at age 18 years, BMI ≥ 25.0 at age 18 years was associated with higher PTC risk (odds ratio [OR] = 4.31, 95% confidence interval [CI]: 3.57, 5.22). The association between BMI ≥ 25.0 at age 18 years and PTC risk was stronger among men (OR = 6.65, 95% CI: 4.78, 9.27) than among women (OR = 3.49, 95% CI: 2.74, 4.43), and stronger among individuals with current BMI ≥ 25.0 (OR = 8.21, 95% CI: 6.34, 10.62) than among those with current BMI < 25.0 (OR = 2.21, 95% CI: 1.49, 3.27). Among PTC patients, BMI ≥ 25.0 at age 18 years was associated with extra-thyroidal extension and T stage ≥2, but not with N stage ≥1 or BRAF

Indexed as

AdolescentAge FactorsBody Mass IndexBody Weight MaintenanceCase-Control StudiesHumansMiddle AgedPediatric ObesityRiskThyroid Cancer, PapillaryThyroid Neoplasms

Identifiers

PMID32193459
PMCPMC7081310

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.