Evidence map›Paper›PMID 32193445›Full record

ArticleScientific reports2020

Mixtures of prion substrains in natural scrapie cases revealed by ovinised murine models.

Tomás Barrio, Hicham Filali, Alicia Otero, Jessica Sheleby-Elías, Belén Marín, Enric Vidal, Vincent Béringue, Juan María Torres, Martin Groschup, Olivier Andréoletti and 2 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Propagation of distinct CWD prion strains during peripheral and intracerebral challenges of gene-targeted mice.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  6. Article
  7. Emergence of CWD strains.Cell and tissue research · 2023
    Review
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 3 countries.

Tomás BarrioCentro de Encefalopatías y Enfermedades Transmisibles Emergentes, Facultad de Veterinaria, Instituto Agroalimentario de Aragón - IA2 (Universidad de Zaragoza - CITA), 50013, Zaragoza, Spain.
Hicham FilaliCentro de Encefalopatías y Enfermedades Transmisibles Emergentes, Facultad de Veterinaria, Instituto Agroalimentario de Aragón - IA2 (Universidad de Zaragoza - CITA), 50013, Zaragoza, Spain.
Alicia OteroCentro de Encefalopatías y Enfermedades Transmisibles Emergentes, Facultad de Veterinaria, Instituto Agroalimentario de Aragón - IA2 (Universidad de Zaragoza - CITA), 50013, Zaragoza, Spain.
Jessica Sheleby-ElíasCentro de Encefalopatías y Enfermedades Transmisibles Emergentes, Facultad de Veterinaria, Instituto Agroalimentario de Aragón - IA2 (Universidad de Zaragoza - CITA), 50013, Zaragoza, Spain.
Belén MarínCentro de Encefalopatías y Enfermedades Transmisibles Emergentes, Facultad de Veterinaria, Instituto Agroalimentario de Aragón - IA2 (Universidad de Zaragoza - CITA), 50013, Zaragoza, Spain.
Enric VidalPriocat Laboratory, Centre de Recerca en Sanitat Animal (CReSA), UAB-IRTA, Universitat Autònoma de Barcelona (UAB), 08193, Bellaterra, Barcelona, Spain.
Vincent BéringueUMR Virologie Immunologie Moléculaires (VIM-UR892), INRA, Université Paris-Saclay, 78352, Jouy-en-Josas, France.
Juan María TorresCentro de Investigación en Sanidad Animal, CISA-INIA, 28130, Valdeolmos, Madrid, Spain.
Martin GroschupInstitute of Novel and Emerging Infectious Diseases, Friedrich-Loeffler-Institute, Südufer 10, 17493, Greifswald-Isle of Riems, Germany.
Olivier AndréolettiUMR INRA ENVT 1225- IHAP, École Nationale Vétérinaire de Toulouse, 31076, Toulouse, France.
Juan José BadiolaCentro de Encefalopatías y Enfermedades Transmisibles Emergentes, Facultad de Veterinaria, Instituto Agroalimentario de Aragón - IA2 (Universidad de Zaragoza - CITA), 50013, Zaragoza, Spain.
Rosa BoleaCentro de Encefalopatías y Enfermedades Transmisibles Emergentes, Facultad de Veterinaria, Instituto Agroalimentario de Aragón - IA2 (Universidad de Zaragoza - CITA), 50013, Zaragoza, Spain. rbolea@unizar.es.
Universidad de Zaragoza · ESCentro de Investigación y Tecnología Agroalimentaria de Aragón · ESCentre de Recerca en Sanitat Animal · ESFriedrich-Loeffler-Institut · DEInstitut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement · FRInteraction Hôtes Agents Pathogènes · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Phenotypic variability in prion diseases, such as scrapie, is associated to the existence of prion strains, which are different pathogenic prion protein (PrP

Indexed as

AnimalsBrainCattleDisease Models, AnimalFranceMice, TransgenicPrion ProteinsPrPSc ProteinsScrapieSheepSpainPrion ProteinsPrPSc Proteins

Identifiers

PMID32193445
PMCPMC7081250
OpenAlexW3011012803

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.