ArticleNature communications2020
Bringing biocatalytic deuteration into the toolbox of asymmetric isotopic labelling techniques.
Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 86 citations in OpenAlex.
- DInternational journal of molecular sciences · 2026Article
- Stereoselective hydrogen isotope exchange on nicotinamide cofactors through flavoenzyme microscopic reversibility.Chemical science · 2026Article
- Employing AC and DC Electrolysis to Modulate Electroenzymatic Pathways for Efficient and Stereoselective H-D Exchange.Journal of the American Chemical Society · 2026Article
- Asymmetric Decarboxylative Protonation and Deuteration of Cyanoacetic Acids Using an Organometallic Proton Shuttle.Journal of the American Chemical Society · 2026Article
- Electricity-driven site-selective deuteration of pharmaceuticals.Chemical science · 2026Article
- Total Syntheses of Deuterated Drugs: A Comprehensive Review.Topics in current chemistry (Cham) · 2025Review
- The Enzymatic Synthesis of Perdeuterated D- and L-Lactic Acid-Bioengineering (Basel, Switzerland) · 2025Article
- Binuclear Lanthanide Complexes as Magnetic Resonance and Optical Imaging Probes for Redox Sensing.Chemistry (Weinheim an der Bergstrasse, Germany) · 2025Article
- Atroposelective [4+1] annulation for the synthesis of isotopic isoindolinones bearing both central and axial chirality.Chemical science · 2025Article
- Enzyme Catalysis for Sustainable Value Creation Using Renewable Biobased Resources.Molecules (Basel, Switzerland) · 2024Review
- Hydrogen isotope labeling unravels origin of soil-bound organic contaminant residues in biodegradability testing.Nature communications · 2024Article
- Selective hydrogenation of nitro compounds to amines by coupled redox reactions over a heterogeneous biocatalyst.Nature communications · 2024Article
- Simple and Efficient Enantioselective α-Deuteration Method of α-Amino Acids without External Chiral Sources.JACS Au · 2024Article
- Review
- Stereoselective Biocatalytic α-Deuteration of L-Amino Acids by a Pyridoxal 5'-Phosphate-Dependent Mannich Cyclase.Chembiochem : a European journal of chemical biology · 2023Article
- Biocatalytic reductive amination as a route to isotopically labelled amino acids suitable for analysis of large proteins by NMR.Chemical science · 2023Article
- Article
- Synthesis of Metabolites and Metabolite-like Compounds Using Biocatalytic Systems.Metabolites · 2023Review
- Hydrogenative alkene perdeuteration aided by a transient cooperative ligand.Nature chemistry · 2023Article
- Deuterium in drug discovery: progress, opportunities and challenges.Nature reviews. Drug discovery · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Enzymes dependent on nicotinamide cofactors are important components of the expanding range of asymmetric synthetic techniques. New challenges in asymmetric catalysis are arising in the field of deuterium labelling, where compounds bearing deuterium (
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.