Evidence map›Paper›PMID 32193379›Full record

ArticleNature communications2020

Ca

Fabian Grein, Anna Müller, Katharina M Scherer, Xinliang Liu, Kevin C Ludwig, Anna Klöckner, Manuel Strach, Hans-Georg Sahl, Ulrich Kubitscheck, Tanja Schneider

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 128 papers.

0numbers the graph read from it
0cells of the map it votes in
128citing papers in PubMed
3.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

128 citing papers in PubMed, 229 citations in OpenAlex.

  1. Article
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  8. A two-component system signaling hub controls enterococcal membrane remodeling in response to daptomycin.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  9. Bacterial cell envelope-targeting antibiotics.Nature reviews. Microbiology · 2026
    Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Frontiers in cellular and infection microbiology · 2026
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Expression ofmBio · 2025
    Article

68 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Fabian Grein *Institute for Pharmaceutical Microbiology, University Hospital Bonn, University of Bonn, Bonn, Germany.ORCID http://orcid.org/0000-0001-8394-8961
Anna Müller *Institute for Pharmaceutical Microbiology, University Hospital Bonn, University of Bonn, Bonn, Germany.ORCID http://orcid.org/0000-0001-6420-3868
Katharina M Scherer *Institute for Physical and Theoretical Chemistry, University of Bonn, Bonn, Germany.ORCID http://orcid.org/0000-0002-2042-5407
Xinliang LiuInstitute for Physical and Theoretical Chemistry, University of Bonn, Bonn, Germany.
Kevin C LudwigInstitute for Pharmaceutical Microbiology, University Hospital Bonn, University of Bonn, Bonn, Germany.
Anna KlöcknerInstitute for Pharmaceutical Microbiology, University Hospital Bonn, University of Bonn, Bonn, Germany.
Manuel StrachInstitute for Pharmaceutical Microbiology, University Hospital Bonn, University of Bonn, Bonn, Germany.
Hans-Georg SahlInstitute of Medical Microbiology, Immunology and Parasitology, University Hospital Bonn, University of Bonn, Bonn, Germany.
Ulrich KubitscheckInstitute for Physical and Theoretical Chemistry, University of Bonn, Bonn, Germany. u.kubitscheck@uni-bonn.de.ORCID http://orcid.org/0000-0003-3750-5355
Tanja SchneiderInstitute for Pharmaceutical Microbiology, University Hospital Bonn, University of Bonn, Bonn, Germany. tschneider@uni-bonn.de.
University of Bonn · DEUniversity Hospital Bonn · DE

Funding

Mechanisms and use of penicillin-binding protein inhibition to optimize cationic peptide anti-MRSA treatmentR01AI132627 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI ROSE, WARREN E · 2017 to 2021
$2.1M
NIAID NIH HHS R01 AI132627
6 · The paper itself

Abstract

The lipopeptide daptomycin is used as an antibiotic to treat severe infections with gram-positive pathogens, such as methicillin resistant Staphylococcus aureus (MRSA) and drug-resistant enterococci. Its precise mechanism of action is incompletely understood, and a specific molecular target has not been identified. Here we show that Ca

Indexed as

Anti-Bacterial AgentsBiosynthetic PathwaysCell WallDaptomycinHumansMembrane LipidsMembranes, ArtificialMethicillin-Resistant Staphylococcus aureusMicrobial Sensitivity TestsPhosphatidylglycerolsPolyisoprenyl PhosphatesStaphylococcal InfectionsAnti-Bacterial AgentsDaptomycinMembrane LipidsMembranes, ArtificialPhosphatidylglycerolsPolyisoprenyl Phosphatesundecaprenyl phosphateundecaprenyl pyrophosphate

Identifiers

PMID32193379
PMCPMC7081307
OpenAlexW3012427533

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.