Evidence map›Paper›PMID 32193350›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2020

Nonuniform growth and surface friction determine bacterial biofilm morphology on soft substrates.

Chenyi Fei, Sheng Mao, Jing Yan, Ricard Alert, Howard A Stone, Bonnie L Bassler, Ned S Wingreen, Andrej Košmrlj

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers.

0numbers the graph read from it
0cells of the map it votes in
71citing papers in PubMed
10.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

71 citing papers in PubMed, 149 citations in OpenAlex.

  1. [Effect of hypochloric acid onZhonghua shao shang yu chuang mian xiu fu za zhi · 2022
    Trial
  2. Article
  3. Mesolens imaging in microbiology.Essays in biochemistry · 2026
    Review
  4. Morphogenesis of bacterial colonies in liquid crystalline environments.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  5. Article
  6. Article
  7. Geometric ordering in bacterial communities.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  8. Article
  9. Formation of a swelling gel underlies a morphological transition inbioRxiv : the preprint server for biology · 2026
    Article
  10. Article
  11. Article
  12. Cilia-driven epithelial folding and unfolding in an early diverging animal.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  13. Review
  14. Article
  15. Article
  16. Colony pattern multistability emerges from a bistable switch.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  17. Article
  18. Article
  19. Article
  20. Article

11 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Chenyi FeiDepartment of Molecular Biology, Princeton University, Princeton, NJ 08544.
Sheng MaoDepartment of Mechanical and Aerospace Engineering, Princeton University, Princeton, NJ 08544.
Jing YanDepartment of Molecular Biology, Princeton University, Princeton, NJ 08544.
Ricard AlertLewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ 08544.ORCID 0000-0002-1885-9177
Howard A StoneDepartment of Mechanical and Aerospace Engineering, Princeton University, Princeton, NJ 08544.
Bonnie L BasslerDepartment of Molecular Biology, Princeton University, Princeton, NJ 08544.ORCID 0000-0002-0043-746X
Ned S WingreenDepartment of Molecular Biology, Princeton University, Princeton, NJ 08544; andrej@princeton.edu wingreen@princeton.edu.
Andrej KošmrljDepartment of Mechanical and Aerospace Engineering, Princeton University, Princeton, NJ 08544; andrej@princeton.edu wingreen@princeton.edu.ORCID 0000-0001-6137-9200
Princeton University · USHoward Hughes Medical Institute · US

Funding

Thermally robust chemotaxis and thermotaxis in Escherichia coliR01GM082938 · NIGMS · PRINCETON UNIVERSITY · PI WINGREEN, NED S · 2008 to 2025
$5.5M
Intra- and Inter- Species Communication in BacteriaR37GM065859 · NIGMS · PRINCETON UNIVERSITY · PI BASSLER, BONNIE L · 2016 to 2025
$3.4M
Function of DepTOR in T Cell Activation and AlloimmunityR21AI114223 · NIAID · BOSTON CHILDREN'S HOSPITAL · PI BRISCOE, DAVID M. · 2014 to 2015
$485k
Quantitative Imaging and Analysis of Bacterial Biofilms from the Single Cell to the CollectiveR21AI146223 · NIAID · PRINCETON UNIVERSITY · PI BASSLER, BONNIE L, STONE, HOWARD · 2019 to 2020
$446k
Howard Hughes Medical InstituteNIAID NIH HHS R21 AI114223NIGMS NIH HHS R01 GM082938NIGMS NIH HHS R37 GM065859
6 · The paper itself

Abstract

During development, organisms acquire three-dimensional (3D) shapes with important physiological consequences. While basic mechanisms underlying morphogenesis are known in eukaryotes, it is often difficult to manipulate them in vivo. To circumvent this issue, here we present a study of developing

Indexed as

AgarAnisotropyBiofilmsBiomechanical PhenomenaFrictionStress, MechanicalSurface PropertiesVibrio choleraeAgarbacterial biofilmchemomechanical model of growthVibrio choleraewrinkling instability

Identifiers

PMID32193350
PMCPMC7148565
OpenAlexW3012113367

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.