The genetic architecture of the human cerebral cortex.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

432 citing papers in PubMed, 4 syntheses or guidelines pooled it.

1. Causal inference between neurodevelopmental disorders and brain structure among individuals with congenital heart disease: Insights from meta-analysis and Mendelian randomization.Italian journal of pediatrics · 2026
   Pooled it
2. Association between polygenic risk for Major Depression and brain structure in a mega-analysis of 50,975 participants across 11 studies.Molecular psychiatry · 2026
   Pooled it
3. The Genetic Architecture of the Human Corpus Callosum and its Subregions.Nature communications · 2025
   Pooled it
4. Brain maps of general cognitive functioning: neuroimaging and neurobiological signatures.Translational psychiatry · 2025
   Pooled it
5. Causal effect of thyroid function on cortical brain structure: A two-sample Mendelian randomization study.IBRO neuroscience reports · 2026
   Article
6. Shared Genetic Architecture Between Psychiatric Disorders and Keratoconus: Insights From a Large-Scale Genome-Wide Cross-Trait Analysis.Cornea · 2026
   Article
7. Association of Polygenic Risk Score for Suicidal Behavior With Ventral Prefrontal Morphology in Bipolar Disorder.Bipolar disorders · 2026
   Article
8. Executive functions as a transdiagnostic endophenotype in developmental psychopathology.Molecular psychiatry · 2026
   Review
9. Big data and psychiatry: advances, constraints and future directions.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2026
   Article
10. Neural Cell Models of Specific Reading Disabilities: Identification of Cellular and Transcriptome Alterations.Genes, brain, and behavior · 2026
    Article
11. Growth of White Matter Signal Aberrations and Cortical Changes in Men and Women: A 9-Year Multiple-Time-Point Longitudinal MRI Study in Older Adults.Human brain mapping · 2026
    Article
12. Physical Activity and Adolescent Brain Structure, Mental Health, and Academic Outcomes.JAMA network open · 2026
    Article
13. Lung cancer and altered brain structure: A causal inference based on MR.Medicine · 2026
    Article
14. Parent-Child Cortical Similarity Indexes Multiple Dimensions of Sensitivity in the Association Between Family Environment and Adolescent Internalizing Symptoms.bioRxiv : the preprint server for biology · 2026
    Article
15. Massively parallel assessment of gene regulatory activity at human cortical-structure-associated variants.Nature neuroscience · 2026
    Article
16. Structural brain indicators of cognitive performance in middle and late adulthood: The Human Connectome Project in Aging/Aging Adult Brain Connectome cohort.Neurobiology of aging · 2026
    Article
17. Common alleles associated with connectivity within and across the brain's main functional networks.Nature communications · 2026
    Article
18. Inferring multi-organ genetic connections using imaging and clinical data through Mendelian randomization.Nature biomedical engineering · 2026
    Article
19. Physical Activity Is Associated With Age-Related Differences in Hippocampal Macrostructure and Microstructure in Middle-Aged and Older Adults.Hippocampus · 2026
    Article
20. Early‑life head circumference is causally associated with adult executive function through cortical surface area expansion.Developmental cognitive neuroscience · 2026
    Article

372 more citing papers are in PubMed but not listed here.

Corrections and comments

• Erratum issued
  Erratum for the Research Article "The genetic architecture of the human cerebral cortex," by K. L. Grasby2021

Authors and funding

367 authors.

Funding

Abstract

Indexed as