Evidence map›Paper›PMID 32193275›Full record

ArticleBMJ open2020

Achieving Control of Asthma in Children in Africa (ACACIA): protocol of an observational study of children's lung health in six sub-Saharan African countries.

Gioia Mosler, Victoria Oyenuga, Emmanuel Addo-Yobo, Olayinka Olufunke Adeyeye, Refiloe Masekela, Hilda Angela Mujuru, Rebecca Nantanda, Sarah Rylance, Ismail Ticklay, Jonathan Grigg

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Asthma in African children and adolescents: Burden, barriers, and management strategies.African journal of thoracic and critical care medicine · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Characterising sources of PMThe Lancet. Child & adolescent health · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Severe asthma in South Africa: A literature review and management approach for primary care.South African family practice : official journal of the South African Academy of Family Practice/Primary Care · 2021
    Review
  12. A historical overview of childhood asthma in southern Africa: Are we there yet?African journal of thoracic and critical care medicine · 2021
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 7 countries.

Gioia MoslerCentre for Genomics and Child Health, Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK g.mosler@qmul.ac.uk.ORCID 0000-0002-6900-4080
Victoria OyenugaCentre for Genomics and Child Health, Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
Emmanuel Addo-YoboSchool of Medicine and Dentistry, College of Health Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Olayinka Olufunke AdeyeyeCollege of Medicine, Lagos State University, Ojo, Nigeria.
Refiloe MasekelaPaediatrics and Child Health, Nelson R Mandela School of Clinical Medicine, University of KwaZulu-Natal, Durban, South Africa.
Hilda Angela MujuruCollege of Health Sciences, University of Zimbabwe, Harare, Zimbabwe.
Rebecca NantandaLung Institute, Makerere College of Health Sciences, Makerere University, Kampala, Uganda.
Sarah RylanceMalawi-Liverpool -Wellcome (MLW) Trust Clinical Research Programme, Wellcome Trust, Blantyre, Malawi.
Ismail TicklayCollege of Health Sciences, University of Zimbabwe, Harare, Zimbabwe.
Jonathan GriggCentre for Genomics and Child Health, Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
Queen Mary University of London · GBUniversity of Zimbabwe · ZWKwame Nkrumah University of Science and Technology · GHLagos State University · NGMakerere University · UGUniversity of KwaZulu-Natal · ZAUniversity of Liverpool · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionLittle is known about asthma control in the rising number of African children who suffer from this condition. The Achieving Control of Asthma in Children in Africa (ACACIA) study is an observational study collecting evidence about paediatric asthma in urban areas of Ghana, Malawi, Nigeria, South Africa, Uganda and Zimbabwe. The primary objectives are: (1) to identify 3000 children aged between 12 years and 14 years with asthma symptoms; and (2) to assess their asthma control, current treatment, knowledge of and attitudes to asthma and barriers to achieving good control. Secondary objective is to develop interventions addressing identified barriers to good symptom control. METHODS AND ANALYSIS: Each centre will undertake screening to identify 500 school children with asthma symptoms using questions from the Global Asthma Network's questionnaire. Children identified to have asthma symptoms will fill in a digital survey, including: Asthma Control Test, questions on medication usage and adherence, medical care, the Brief-Illness Perception questionnaire and environmental factors. Exhaled nitric oxide testing and prebronchodilator and postbronchodilator spirometry will be performed. A subgroup of children will participate in focus group discussions. Results will be analysed using descriptive statistics and comparative analysis. Informed by these results, we will assess the feasibility of potential interventions, including the adaption of a UK-based theatre performance about asthma attitudes and digital solutions to improve asthma management. ETHICS AND DISSEMINATION: The ACACIA study has been reviewed by the Queen Mary University of London Ethics of Research Committee in the UK. All African centres have received local ethical approval for this study. Study results will be published in academic journals and at conferences. Study outputs will be communicated to the public via newsfeeds on the ACACIA website and Twitter, and through news media outlets and other local dissemination. TRIAL REGISTRATION NUMBER: 269211.

Indexed as

AsthmaLungAdolescentChildCross-Sectional StudiesGhanaHumansMalawiNigeriaObservational Studies as TopicResearch DesignSouth AfricaUgandaZimbabweasthmamedical education & trainingpaediatric thoracic medicine

Identifiers

PMID32193275
PMCPMC7202730
OpenAlexW3011379006

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.