ArticleAJNR. American journal of neuroradiology2020
Comparison of Enhancement of the Vestibular Perilymph between Variable and Constant Flip Angle-Delayed 3D-FLAIR Sequences in Menière Disease.
Article in AJNR. American journal of neuroradiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
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Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 23 citations in OpenAlex.
- Pooled it
- Delayed post gadolinium MRI descriptors for Meniere's disease: a systematic review and meta-analysis.European radiology · 2023Pooled it
- Enabling unenhanced endolymphatic hydrops MRI: a subtraction method using 3D-FLAIR sequences with different inversion time.European radiology · 2026Article
- Optimal MRI protocol for acute unilateral vestibulopathy: 3D-fsFLAIR vs 3D-fsT1WI at multiple post-contrast time points.European radiology · 2026Article
- Prevalence of Endolymphatic Hydrops Herniation into the Semicircular Canals in Primary Hydropic Ear Disease: Correlation with Clinical and Radiologic Parameters.AJNR. American journal of neuroradiology · 2025Article
- An unenhanced 3D-FLAIR sequence using long repetition time and constant flip angle to image endolymphatic hydrops.European radiology · 2025Article
- Iterative Denoising Accelerated 3D FLAIR Sequence for Hydrops MR Imaging at 3T.AJNR. American journal of neuroradiology · 2023Article
- Comparison between 3D SPACE FLAIR and 3D TSE FLAIR in Menière's disease.Neuroradiology · 2022Article
- A Perspective for Ménière's Disease: In Silico Investigations of Dexamethasone as a Direct Modulator of AQP2.Biomolecules · 2022Article
- T2 relaxation time shortening in the cochlea of patients with sudden sensory neuronal hearing loss: a retrospective study using quantitative synthetic magnetic resonance imaging.European radiology · 2021Article
- Advanced Imaging of the Vestibular Endolymphatic Space in Ménière's Disease.Frontiers in surgery · 2021Review
- Intravenous Delayed Gadolinium-Enhanced MR Imaging of the Endolymphatic Space: A Methodological Comparative Study.Frontiers in neurology · 2021Article
Corrections and comments
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Authors and funding
8 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeEndolymphatic hydrops in patients with Menière disease relies on delayed postcontrast 3D-FLAIR sequences. The purpose of this study was to compare the degree of perilymphatic enhancement and the detection rate of endolymphatic hydrops using constant and variable flip angles sequences. MATERIALS AND
methodsThis was a retrospective study performed in 16 patients with Menière disease who underwent 3T MR imaging 4 hours after gadolinium injection using two 3D-FLAIR sequences with a constant flip angle at 140° for the first and a heavily-T2 variable flip angle for the second. The signal intensity ratio was measured using the ROI method. We graded endolymphatic hydrops and evaluated the cochlear blood-labyrinth barrier impairment.
resultsBoth for symptomatic and asymptomatic ears, the median signal intensity ratio was significantly higher with the constant flip angle than with the heavily-T2 variable flip angle (7.16 versus 1.54 and 7.00 versus 1.45,
conclusions3D-FLAIR constant flip angle sequences provide a higher signal intensity ratio and are superior to heavily-T2 variable flip angle sequences in reliably evaluating the cochlear blood-labyrinth barrier impairment and the endolymphatic space.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.