Evidence map›Paper›PMID 32193048›Full record

Observational studyDrug and alcohol dependence2020

Wearable sensor-based detection of stress and craving in patients during treatment for substance use disorder: A mixed methods pilot study.

Stephanie Carreiro, Keerthi Kumar Chintha, Sloke Shrestha, Brittany Chapman, David Smelson, Premananda Indic

2 registry-linked trialsOpen access · greenAbstract readObservational Study
In one paragraph

Observational study in Drug and alcohol dependence, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 37 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 1 pooled it
6.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05227339 phase2 / phase3completednot on this mapstarted 2022, after this paper: background citation

RAE (Realize, Analyze, Engage)- A Digital Biomarker Based Detection and Intervention System for Stress and Craving During Recovery From Substance Use Disorder: Phase II

TypeinterventionalSponsorContinueYou, LLCRan2022 to 2024Enrolled209ConditionsSubstance Use Disorders, Treatment Adherence and ComplianceArmsRAE
NCT06629467 nacompletednot on this mapstarted 2023, after this paper: background citation

Cognitive Behavioral Treatment With Activity Trackers for Smoking Cessation

TypeinterventionalSponsorUniversity of OviedoRan2023 to 2025Enrolled128ConditionsTobacco Use Cessation, Physical ActivityArmsCognitive-behavioral therapy for smoking cessation, Personalized PA plan, Fitbit Versa 3
3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 1 synthesis or guideline pooled it, 68 citations in OpenAlex.

  1. Anger and substance abuse: a systematic review and meta-analysis.Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999)
    Pooled it
  2. Article
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  7. Detecting Ethanol Intoxication and Impairment Using Wearable Biosensors.Proceedings of the ... Annual Hawaii International Conference on System Sciences. Annual Hawaii International Conference on System Sciences · 2026
    Article
  8. What Are You Craving? Using Wearables to Distinguish Food and Drug Cravings During Treatment with Extended-Release Buprenorphine.Proceedings of the ... Annual Hawaii International Conference on System Sciences. Annual Hawaii International Conference on System Sciences · 2026
    Article
  9. Article
  10. Predicting Craving-Related Emotions among Opioid Use Disorder Patients: Preliminary Results.... International Conference on Wearable and Implantable Body Sensor Networks. International Conference on Wearable and Implantable Body Sensor Networks · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Stephanie CarreiroDepartment of Emergency Medicine, Division of Medical Toxicology, University of Massachusetts Medical School, Worcester, MA, United States. Electronic address: stephanie.carreiro@umassmed.edu.
Keerthi Kumar ChinthaDepartment of Electrical Engineering, University of Texas at Tyler, Tyler, TX, United States.
Sloke ShresthaDepartment of Electrical Engineering, University of Texas at Tyler, Tyler, TX, United States.
Brittany ChapmanDepartment of Emergency Medicine, Division of Medical Toxicology, University of Massachusetts Medical School, Worcester, MA, United States.
David SmelsonDepartment of Psychiatry, Division of Addiction Psychiatry, University of Massachusetts Medical School, Worcester, MA, United States.
Premananda IndicDepartment of Electrical Engineering, University of Texas at Tyler, Tyler, TX, United States.
The University of Texas at Tyler · USUniversity of Massachusetts Chan Medical School · US

Funding

RAE (Realize, Analyze, Engage)- A Digital Biomarker Based Detection and Intervention System for Stress and Craving During Recovery from Substance Abuse DisordersR44DA046151 · NIDA · CONTINUEYOU, LLC · PI CARREIRO, STEPHANIE P, GILBERTSON, NICOLE · 2019 to 2022
$1.8M
iTransform: Wearable Biosensors to Detect the Evolution of Opioid Tolerance in Opioid Naïve IndividualsK23DA045242 · NIDA · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI CARREIRO, STEPHANIE P · 2019 to 2021
$566k
NIDA NIH HHS K23 DA045242NIDA NIH HHS L30 DA038357NIDA NIH HHS R44 DA046151
6 · The paper itself

Abstract

aimsTo determine the accuracy of a wearable sensor to detect and differentiate episodes of self-reported craving and stress in individuals with substance use disorders, and to assess acceptability, barriers, and facilitators to sensor-based monitoring in this population.

methodsThis was an observational mixed methods pilot study. Adults enrolled in an outpatient treatment program for a substance use disorder wore a non-invasive wrist-mounted sensor for four days and self-reported episodes of stress and craving. Continuous physiologic data (accelerometry, skin conductance, skin temperature, and heart rate) were extracted from the sensors and analyzed via various machine learning algorithms. Semi-structured interviews were conducted upon study completion, and thematic analysis was conducted on qualitative data from semi-structured interviews.

resultsThirty individuals completed the protocol, and 43 % (N = 13) were female. A total of 41 craving and 104 stress events were analyzed. The differentiation accuracies of the top performing models were as follows: stress vs. non-stress states 74.5 % (AUC 0.82), craving vs. no-craving 75.7 % (AUC 0.82), and craving vs. stress 76.8 % (AUC 0.8). Overall participant perception was positive, and acceptability was high. Emergent themes from the exit interviews included a perception of connectedness and increased mindfulness related to wearing the sensor, both of which were reported as helpful to recovery. Barriers to engagement included interference with other daily wear items, and perceived stigma.

conclusionsWearable sensors can be used to objectively differentiate episodes of craving and stress, and individuals in recovery from substance use disorder are accepting of continuous monitoring with these devices.

Indexed as

AdolescentAdultAgedAlgorithmsCravingFemaleHeart RateHumansMachine LearningMaleMiddle AgedMindfulnessPilot ProjectsSelf ReportStress, PsychologicalSubstance-Related DisordersCravingmHealthSensorStressSubstance use disorderWearable

Identifiers

PMID32193048
PMCPMC7197459
OpenAlexW3010584756

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.